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DJ-1 Alleviates Neuroinflammation and the Related Blood-Spinal Cord Barrier Destruction by Suppressing NLRP3 Inflammasome Activation via SOCS1/Rac1/ROS Pathway in a Rat Model of Traumatic Spinal Cord Injury
DJ-1 has been shown to play essential roles in neuronal protection and anti-inflammation in nervous system diseases. This study aimed to explore how DJ-1 regulates neuroinflammation after traumatic spinal cord injury (t-SCI). The rat model of spinal cord injury was established by the clamping method...
Autores principales: | Cai, Lingxin, Gao, Liansheng, Zhang, Guoqiang, Zeng, Hanhai, Wu, Xinyan, Tan, Xiaoxiao, Qian, Cong, Chen, Gao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267719/ https://www.ncbi.nlm.nih.gov/pubmed/35807002 http://dx.doi.org/10.3390/jcm11133716 |
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