Cargando…

Dynamic Metabolic Changes During Prolonged Ex Situ Heart Perfusion Are Associated With Myocardial Functional Decline

Ex situ heart perfusion (ESHP) was developed to preserve and evaluate donated hearts in a perfused beating state. However, myocardial function declines during ESHP, which limits the duration of perfusion and the potential to expand the donor pool. In this research, we combine a novel, minimally-inva...

Descripción completa

Detalles Bibliográficos
Autores principales:	Olkowicz, Mariola, Ribeiro, Roberto Vanin Pinto, Yu, Frank, Alvarez, Juglans Souto, Xin, Liming, Yu, Miao, Rosales, Roizar, Adamson, Mitchell Brady, Bissoondath, Ved, Smolenski, Ryszard T., Billia, Filio, Badiwala, Mitesh Vallabh, Pawliszyn, Janusz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267769/ https://www.ncbi.nlm.nih.gov/pubmed/35812438 http://dx.doi.org/10.3389/fimmu.2022.859506

Ejemplares similares

Heart Failure and Drug Therapies: A Metabolic Review
por: Yu, Frank, et al.
Publicado: (2022)

Echocardiographic assessment of left ventricular function in ex situ heart perfusion using pump-supported and passive afterload working mode: a pilot study
por: Hondjeu, Arnaud Romeo Mbadjeu, et al.
Publicado: (2021)

Left Ventricular Assist Device With a Left Atrial Inflow Cannula for Hypertrophic Cardiomyopathy
por: Kiamanesh, Omid, et al.
Publicado: (2020)

The metabolic fate of oxaliplatin in the biological milieu investigated during in vivo lung perfusion using a unique miniaturized sampling approach based on solid-phase microextraction coupled with liquid chromatography-mass spectrometry
por: Olkowicz, Mariola, et al.
Publicado: (2022)

SPME-LC/MS-based serum metabolomic phenotyping for distinguishing ovarian cancer histologic subtypes: a pilot study
por: Olkowicz, Mariola, et al.
Publicado: (2021)

High Throughput Procedure for Comparative Analysis of In Vivo Cardiac Glucose or Amino Acids Use in Cardiovascular Pathologies and Pharmacological Treatments
por: Tomczyk, Marta, et al.
Publicado: (2021)

Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans
por: Olkowicz, Mariola, et al.
Publicado: (2021)

Physical Activity and Inhibition of ACE Additively Modulate ACE/ACE-2 Balance in Heart Failure in Mice
por: Tyrankiewicz, Urszula, et al.
Publicado: (2021)

Solid phase microextraction chemical biopsy tool for monitoring of doxorubicin residue during in vivo lung chemo-perfusion
por: Bojko, Barbara, et al.
Publicado: (2021)

Functional and Biochemical Endothelial Profiling In Vivo in a Murine Model of Endothelial Dysfunction; Comparison of Effects of 1-Methylnicotinamide and Angiotensin-converting Enzyme Inhibitor
por: Bar, Anna, et al.
Publicado: (2017)

Myocardial recovery following durable left ventricular assist device support
por: Rao, Vivek, et al.
Publicado: (2021)

Impact of Different Clinical Perfusates During Normothermic Ex Situ Liver Perfusion on Pig Liver Transplant Outcomes in a DCD Model
por: Linares-Cervantes, Ivan, et al.
Publicado: (2019)

Metabolomic fingerprinting of porcine lung tissue during pre-clinical prolonged ex vivo lung perfusion using in vivo SPME coupled with LC-HRMS
por: Looby, Nikita, et al.
Publicado: (2022)

Erratum to: Echocardiography for adult patients supported with extracorporeal membrane oxygenation
por: Douflé, Ghislaine, et al.
Publicado: (2016)

Echocardiography for adult patients supported with extracorporeal membrane oxygenation
por: Douflé, Ghislaine, et al.
Publicado: (2015)

Could Clonal Hematopoiesis Explain the Link Between Increased Cancer Mortality Incidence in Heart Failure?
por: Brahmbhatt, Darshan H., et al.
Publicado: (2022)

Patient perceptions of implantable cardioverter-defibrillator deactivation discussions: A qualitative study
por: MacIver, Jane, et al.
Publicado: (2016)

In vivo solid phase microextraction for therapeutic monitoring and pharmacometabolomic fingerprinting of lung during in vivo lung perfusion of FOLFOX
por: Looby, Nikita, et al.
Publicado: (2023)

LVAD therapy as a catalyst to heart failure remission and myocardial recovery
por: Hamad, Eman A., et al.
Publicado: (2023)

Cardiovascular Collapse in COVID-19 Infection: The Role of Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO)
por: Chow, Justin, et al.
Publicado: (2020)

Proposal for an Ambulatory Heart Failure Management Curriculum for Cardiology Residency Training Programs
por: Almufleh, Aws, et al.
Publicado: (2022)

Prediction, prevention, and management of right ventricular failure after left ventricular assist device implantation: A comprehensive review
por: Rodenas-Alesina, Eduard, et al.
Publicado: (2022)

In Vivo Solid-Phase Microextraction and Applications in Environmental Sciences
por: Yu, Miao, et al.
Publicado: (2021)

The changing landscape of left ventricular assist device care in the setting of a pandemic
por: Amadio, Jennifer M., et al.
Publicado: (2020)

Inhibitory activity of chokeberry, bilberry, raspberry and cranberry polyphenol-rich extract towards adipogenesis and oxidative stress in differentiated 3T3-L1 adipose cells
por: Kowalska, Katarzyna, et al.
Publicado: (2017)

Pericardial waffle for effusive‐constrictive pericarditis
por: Kiamanesh, Omid, et al.
Publicado: (2020)

AMP-regulated protein kinase activity in the hearts of mice treated with low- or high-fat diet measured using novel LC–MS method
por: Rybakowska, I. M., et al.
Publicado: (2015)

Time-course monitoring of in vitro biotransformation reaction via solid-phase microextraction-ambient mass spectrometry approaches
por: Jaroch, Karol, et al.
Publicado: (2022)

The E3 ligase Mule protects the heart against oxidative stress and mitochondrial dysfunction through Myc-dependent inactivation of Pgc-1α and Pink1
por: Dadson, Keith, et al.
Publicado: (2017)

ROS Modulating Effects of Lingonberry (Vaccinium vitis-idaea L.) Polyphenols on Obese Adipocyte Hypertrophy and Vascular Endothelial Dysfunction
por: Kowalska, Katarzyna, et al.
Publicado: (2021)

Descending aortic thrombosis and acute type B dissection during central extracorporeal membrane oxygenation: A word of caution
por: Fukunaga, Naoto, et al.
Publicado: (2020)

Cardiac-specific ablation of the E3 ubiquitin ligase Mdm2 leads to oxidative stress, broad mitochondrial deficiency and early death
por: Hauck, Ludger, et al.
Publicado: (2017)

Point-of-Care Ultrasound: A Case Series of Potential Pitfalls
por: Douflé, Ghislaine, et al.
Publicado: (2022)

Elderberry (Sambucus nigra L.) Fruit Extract Alleviates Oxidative Stress, Insulin Resistance, and Inflammation in Hypertrophied 3T3-L1 Adipocytes and Activated RAW 264.7 Macrophages
por: Zielińska-Wasielica, Joanna, et al.
Publicado: (2019)

Metabolic profiling of plasma from cardiac surgical patients concurrently administered with tranexamic acid: DI-SPME–LC–MS analysis
por: Bojko, Barbara, et al.
Publicado: (2014)

Solid-phase microextraction of endogenous metabolites from intact tissue validated using a Biocrates standard reference method kit
por: Jiang, Runshan Will, et al.
Publicado: (2023)

Platelet preservation in cardiac surgery using minimally invasive extracorporeal circulation versus optimized cardiopulmonary bypass
por: Beairsto, Brian, et al.
Publicado: (2022)

The Saliva Exposome for Monitoring of Individuals’ Health Trajectories
por: Bessonneau, Vincent, et al.
Publicado: (2017)

Tissue storage affects lipidome profiling in comparison to in vivo microsampling approach
por: Roszkowska, Anna, et al.
Publicado: (2018)

The use of solid phase microextraction for metabolomic analysis of non-small cell lung carcinoma cell line (A549) after administration of combretastatin A4
por: Jaroch, Karol, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_u9d51kdokb9cdff5psb4ckvo92