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Achilles Tendon Rupture and Dysmetabolic Diseases: A Multicentric, Epidemiologic Study

Introduction: Achilles tendon ruptures are common. Metabolic disorders, such as diabetes mellitus, hypercholesterolemia, thyroid disorders, and obesity, impair tendons health, leading to Achilles tendinopathy and likely predisposing patients to Achilles tendon ruptures. Materials and methods: Patien...

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Autores principales: Oliva, Francesco, Marsilio, Emanuela, Asparago, Giovanni, Giai Via, Alessio, Biz, Carlo, Padulo, Johnny, Spoliti, Marco, Foti, Calogero, Oliva, Gabriella, Mannarini, Stefania, Rossi, Alessandro Alberto, Ruggieri, Pietro, Maffulli, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267833/
https://www.ncbi.nlm.nih.gov/pubmed/35806982
http://dx.doi.org/10.3390/jcm11133698
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author Oliva, Francesco
Marsilio, Emanuela
Asparago, Giovanni
Giai Via, Alessio
Biz, Carlo
Padulo, Johnny
Spoliti, Marco
Foti, Calogero
Oliva, Gabriella
Mannarini, Stefania
Rossi, Alessandro Alberto
Ruggieri, Pietro
Maffulli, Nicola
author_facet Oliva, Francesco
Marsilio, Emanuela
Asparago, Giovanni
Giai Via, Alessio
Biz, Carlo
Padulo, Johnny
Spoliti, Marco
Foti, Calogero
Oliva, Gabriella
Mannarini, Stefania
Rossi, Alessandro Alberto
Ruggieri, Pietro
Maffulli, Nicola
author_sort Oliva, Francesco
collection PubMed
description Introduction: Achilles tendon ruptures are common. Metabolic disorders, such as diabetes mellitus, hypercholesterolemia, thyroid disorders, and obesity, impair tendons health, leading to Achilles tendinopathy and likely predisposing patients to Achilles tendon ruptures. Materials and methods: Patients who visited the Orthopedic Outpatient Clinics and the Accident and Emergency Departments of five different hospitals in Italy were recruited. Through telephone interviews, we administered a questionnaire to all the patients who had undergone surgical ATR repair, evaluating their past medical history, sport- and work-related activities, drug use, and post-operative rehabilitation outcomes. Results: “Return to work activities/sport” was negatively predicted by the presence of a metabolic disorder (β = −0.451; OR = 0.637) and ‘open’ surgery technique (β = −0.389; OR = 0.678). “Medical complications” were significantly predicted by metabolic disorders (β = 0.600 (0.198); OR = 1.822) and was negatively related to ‘mini-invasive’ surgery (i.e., not ‘open’ nor ‘percutaneous’) (β = −0.621; OR = 0.537). “Immediate weightbearing” and “immediate walking without assistance” were negatively predicted by ‘open’ technique (β = −0.691; OR = 0.501 and β = −0.359 (0.174; OR = 0.698)). Conclusions: Metabolic conditions can strongly affect post-operative outcomes following surgical repair of acute Achilles tendon tears.
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spelling pubmed-92678332022-07-09 Achilles Tendon Rupture and Dysmetabolic Diseases: A Multicentric, Epidemiologic Study Oliva, Francesco Marsilio, Emanuela Asparago, Giovanni Giai Via, Alessio Biz, Carlo Padulo, Johnny Spoliti, Marco Foti, Calogero Oliva, Gabriella Mannarini, Stefania Rossi, Alessandro Alberto Ruggieri, Pietro Maffulli, Nicola J Clin Med Article Introduction: Achilles tendon ruptures are common. Metabolic disorders, such as diabetes mellitus, hypercholesterolemia, thyroid disorders, and obesity, impair tendons health, leading to Achilles tendinopathy and likely predisposing patients to Achilles tendon ruptures. Materials and methods: Patients who visited the Orthopedic Outpatient Clinics and the Accident and Emergency Departments of five different hospitals in Italy were recruited. Through telephone interviews, we administered a questionnaire to all the patients who had undergone surgical ATR repair, evaluating their past medical history, sport- and work-related activities, drug use, and post-operative rehabilitation outcomes. Results: “Return to work activities/sport” was negatively predicted by the presence of a metabolic disorder (β = −0.451; OR = 0.637) and ‘open’ surgery technique (β = −0.389; OR = 0.678). “Medical complications” were significantly predicted by metabolic disorders (β = 0.600 (0.198); OR = 1.822) and was negatively related to ‘mini-invasive’ surgery (i.e., not ‘open’ nor ‘percutaneous’) (β = −0.621; OR = 0.537). “Immediate weightbearing” and “immediate walking without assistance” were negatively predicted by ‘open’ technique (β = −0.691; OR = 0.501 and β = −0.359 (0.174; OR = 0.698)). Conclusions: Metabolic conditions can strongly affect post-operative outcomes following surgical repair of acute Achilles tendon tears. MDPI 2022-06-27 /pmc/articles/PMC9267833/ /pubmed/35806982 http://dx.doi.org/10.3390/jcm11133698 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Oliva, Francesco
Marsilio, Emanuela
Asparago, Giovanni
Giai Via, Alessio
Biz, Carlo
Padulo, Johnny
Spoliti, Marco
Foti, Calogero
Oliva, Gabriella
Mannarini, Stefania
Rossi, Alessandro Alberto
Ruggieri, Pietro
Maffulli, Nicola
Achilles Tendon Rupture and Dysmetabolic Diseases: A Multicentric, Epidemiologic Study
title Achilles Tendon Rupture and Dysmetabolic Diseases: A Multicentric, Epidemiologic Study
title_full Achilles Tendon Rupture and Dysmetabolic Diseases: A Multicentric, Epidemiologic Study
title_fullStr Achilles Tendon Rupture and Dysmetabolic Diseases: A Multicentric, Epidemiologic Study
title_full_unstemmed Achilles Tendon Rupture and Dysmetabolic Diseases: A Multicentric, Epidemiologic Study
title_short Achilles Tendon Rupture and Dysmetabolic Diseases: A Multicentric, Epidemiologic Study
title_sort achilles tendon rupture and dysmetabolic diseases: a multicentric, epidemiologic study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267833/
https://www.ncbi.nlm.nih.gov/pubmed/35806982
http://dx.doi.org/10.3390/jcm11133698
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