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Hepatic Expression of the Na(+)-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation
The hepatic Na(+)-taurocholate cotransporting polypeptide NTCP/SLC10A1 is important for the uptake of bile salts and selected drugs. Its inhibition results in increased systemic bile salt concentrations. NTCP is also the entry receptor for the hepatitis B/D virus. We investigated interindividual hep...
Autores principales: | Tremmel, Roman, Nies, Anne T., van Eijck, Barbara A. C., Handin, Niklas, Haag, Mathias, Winter, Stefan, Büttner, Florian A., Kölz, Charlotte, Klein, Franziska, Mazzola, Pascale, Hofmann, Ute, Klein, Kathrin, Hoffmann, Per, Nöthen, Markus M., Gaugaz, Fabienne Z., Artursson, Per, Schwab, Matthias, Schaeffeler, Elke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267852/ https://www.ncbi.nlm.nih.gov/pubmed/35806468 http://dx.doi.org/10.3390/ijms23137468 |
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