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Hepatic Expression of the Na(+)-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation

The hepatic Na(+)-taurocholate cotransporting polypeptide NTCP/SLC10A1 is important for the uptake of bile salts and selected drugs. Its inhibition results in increased systemic bile salt concentrations. NTCP is also the entry receptor for the hepatitis B/D virus. We investigated interindividual hep...

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Detalles Bibliográficos
Autores principales: Tremmel, Roman, Nies, Anne T., van Eijck, Barbara A. C., Handin, Niklas, Haag, Mathias, Winter, Stefan, Büttner, Florian A., Kölz, Charlotte, Klein, Franziska, Mazzola, Pascale, Hofmann, Ute, Klein, Kathrin, Hoffmann, Per, Nöthen, Markus M., Gaugaz, Fabienne Z., Artursson, Per, Schwab, Matthias, Schaeffeler, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267852/
https://www.ncbi.nlm.nih.gov/pubmed/35806468
http://dx.doi.org/10.3390/ijms23137468

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