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Reliable Prediction of Post-Operative Complications’ Rate Using the G8 Screening Tool: A Prospective Study on Elderly Patients Undergoing Surgery for Kidney Cancer

In the last years the incidence of renal neoplasms has been steadily increasing, along with the average age of patients at the time of diagnosis. Surgical management for localized disease is becoming more challenging because of patients’ frailty. We conducted a multi-center prospective study to eval...

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Autores principales: Traunero, Fabio, Claps, Francesco, Silvestri, Tommaso, Mir, Maria Carmen, Ongaro, Luca, Rizzo, Michele, Piasentin, Andrea, Liguori, Giovanni, Vedovo, Francesca, Celia, Antonio, Trombetta, Carlo, Pavan, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267910/
https://www.ncbi.nlm.nih.gov/pubmed/35807070
http://dx.doi.org/10.3390/jcm11133785
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author Traunero, Fabio
Claps, Francesco
Silvestri, Tommaso
Mir, Maria Carmen
Ongaro, Luca
Rizzo, Michele
Piasentin, Andrea
Liguori, Giovanni
Vedovo, Francesca
Celia, Antonio
Trombetta, Carlo
Pavan, Nicola
author_facet Traunero, Fabio
Claps, Francesco
Silvestri, Tommaso
Mir, Maria Carmen
Ongaro, Luca
Rizzo, Michele
Piasentin, Andrea
Liguori, Giovanni
Vedovo, Francesca
Celia, Antonio
Trombetta, Carlo
Pavan, Nicola
author_sort Traunero, Fabio
collection PubMed
description In the last years the incidence of renal neoplasms has been steadily increasing, along with the average age of patients at the time of diagnosis. Surgical management for localized disease is becoming more challenging because of patients’ frailty. We conducted a multi-center prospective study to evaluate the role of the G8 as a screening tool in the assessment of intra and post-operative complications of elderly patients (≥70 y.o.) undergoing surgery for kidney cancer. A total of 162 patients were prospectively enrolled between January 2015 to January 2019 and divided into two study groups (frail vs. not-frail) according to their geriatric risk profile based on G8 score. Several factors (i.e., age, CCI, ASA score, preoperative anemia, RENAL score, surgical procedures, and techniques) were analyzed to identify whether any of them would configure as a statistically significant predictor of surgical complications. According to the G8 Score, 90 patients were included in the frail group. A total of 52 frail patients vs. 4 non-frail patients developed a postoperative complication of any kind (p < 0.001). Of these, 11 were major complications and all occurred in the frail group. Our results suggest that the G8 screening tool is an effective and useful instrument to predict the risk of overall complications in elderly patients prior to renal surgery.
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spelling pubmed-92679102022-07-09 Reliable Prediction of Post-Operative Complications’ Rate Using the G8 Screening Tool: A Prospective Study on Elderly Patients Undergoing Surgery for Kidney Cancer Traunero, Fabio Claps, Francesco Silvestri, Tommaso Mir, Maria Carmen Ongaro, Luca Rizzo, Michele Piasentin, Andrea Liguori, Giovanni Vedovo, Francesca Celia, Antonio Trombetta, Carlo Pavan, Nicola J Clin Med Article In the last years the incidence of renal neoplasms has been steadily increasing, along with the average age of patients at the time of diagnosis. Surgical management for localized disease is becoming more challenging because of patients’ frailty. We conducted a multi-center prospective study to evaluate the role of the G8 as a screening tool in the assessment of intra and post-operative complications of elderly patients (≥70 y.o.) undergoing surgery for kidney cancer. A total of 162 patients were prospectively enrolled between January 2015 to January 2019 and divided into two study groups (frail vs. not-frail) according to their geriatric risk profile based on G8 score. Several factors (i.e., age, CCI, ASA score, preoperative anemia, RENAL score, surgical procedures, and techniques) were analyzed to identify whether any of them would configure as a statistically significant predictor of surgical complications. According to the G8 Score, 90 patients were included in the frail group. A total of 52 frail patients vs. 4 non-frail patients developed a postoperative complication of any kind (p < 0.001). Of these, 11 were major complications and all occurred in the frail group. Our results suggest that the G8 screening tool is an effective and useful instrument to predict the risk of overall complications in elderly patients prior to renal surgery. MDPI 2022-06-30 /pmc/articles/PMC9267910/ /pubmed/35807070 http://dx.doi.org/10.3390/jcm11133785 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Traunero, Fabio
Claps, Francesco
Silvestri, Tommaso
Mir, Maria Carmen
Ongaro, Luca
Rizzo, Michele
Piasentin, Andrea
Liguori, Giovanni
Vedovo, Francesca
Celia, Antonio
Trombetta, Carlo
Pavan, Nicola
Reliable Prediction of Post-Operative Complications’ Rate Using the G8 Screening Tool: A Prospective Study on Elderly Patients Undergoing Surgery for Kidney Cancer
title Reliable Prediction of Post-Operative Complications’ Rate Using the G8 Screening Tool: A Prospective Study on Elderly Patients Undergoing Surgery for Kidney Cancer
title_full Reliable Prediction of Post-Operative Complications’ Rate Using the G8 Screening Tool: A Prospective Study on Elderly Patients Undergoing Surgery for Kidney Cancer
title_fullStr Reliable Prediction of Post-Operative Complications’ Rate Using the G8 Screening Tool: A Prospective Study on Elderly Patients Undergoing Surgery for Kidney Cancer
title_full_unstemmed Reliable Prediction of Post-Operative Complications’ Rate Using the G8 Screening Tool: A Prospective Study on Elderly Patients Undergoing Surgery for Kidney Cancer
title_short Reliable Prediction of Post-Operative Complications’ Rate Using the G8 Screening Tool: A Prospective Study on Elderly Patients Undergoing Surgery for Kidney Cancer
title_sort reliable prediction of post-operative complications’ rate using the g8 screening tool: a prospective study on elderly patients undergoing surgery for kidney cancer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267910/
https://www.ncbi.nlm.nih.gov/pubmed/35807070
http://dx.doi.org/10.3390/jcm11133785
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