Design, Synthesis, and Biological Evaluation of N14-Amino Acid-Substituted Tetrandrine Derivatives as Potential Antitumor Agents against Human Colorectal Cancer

As a typical dibenzylisoquinoline alkaloid, tetrandrine (TET) is clinically used for the treatment of silicosis, inflammatory pulmonary, and cardiovascular diseases in China. Recent investigations have demonstrated the outstanding anticancer activity of this structure, but its poor aqueous solubilit...

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Detalles Bibliográficos
Autores principales: Wang, Yu-Chan, Zhang, Rong-Hong, Hu, Sheng-Cao, Zhang, Hong, Yang, Dan, Zhang, Wen-Li, Zhao, Yong-Long, Cui, Dong-Bing, Li, Yong-Jun, Pan, Wei-Dong, Liao, Shang-Gao, Zhou, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268013/
https://www.ncbi.nlm.nih.gov/pubmed/35807286
http://dx.doi.org/10.3390/molecules27134040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268013/
https://www.ncbi.nlm.nih.gov/pubmed/35807286
http://dx.doi.org/10.3390/molecules27134040

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