Chelation of Theranostic Copper Radioisotopes with S-Rich Macrocycles: From Radiolabelling of Copper-64 to In Vivo Investigation

Copper radioisotopes are generally employed for cancer imaging and therapy when firmly coordinated via a chelating agent coupled to a tumor-seeking vector. However, the biologically triggered Cu(2+)-Cu(+) redox switching may constrain the in vivo integrity of the resulting complex, leading to demeta...

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Detalles Bibliográficos
Autores principales: Tosato, Marianna, Verona, Marco, Favaretto, Chiara, Pometti, Marco, Zanoni, Giordano, Scopelliti, Fabrizio, Cammarata, Francesco Paolo, Morselli, Luca, Talip, Zeynep, van der Meulen, Nicholas P., Di Marco, Valerio, Asti, Mattia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268100/
https://www.ncbi.nlm.nih.gov/pubmed/35807404
http://dx.doi.org/10.3390/molecules27134158

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