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Pollen Food Allergy Syndrome in Allergic March

The association between pollen food allergy syndrome (PFAS) and allergic march remains unclear. In this prospective cohort study of the general population in Tokyo (T-Child Study), we found that sensitization to Cry j 1 and Fel d 1 at ages 5 and 9 years was associated with an increased risk of PFAS...

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Autores principales: Yasudo, Hiroki, Yamamoto-Hanada, Kiwako, Yang, Limin, Saito-Abe, Mayako, Sato, Miori, Miyaji, Yumiko, Shimada, Mami, Hirai, Seiko, Toyokuni, Kenji, Ishikawa, Fumi, Inuzuka, Yusuke, Kabashima, Shigenori, Fukuie, Tatsuki, Ohya, Yukihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268136/
https://www.ncbi.nlm.nih.gov/pubmed/35807837
http://dx.doi.org/10.3390/nu14132658
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author Yasudo, Hiroki
Yamamoto-Hanada, Kiwako
Yang, Limin
Saito-Abe, Mayako
Sato, Miori
Miyaji, Yumiko
Shimada, Mami
Hirai, Seiko
Toyokuni, Kenji
Ishikawa, Fumi
Inuzuka, Yusuke
Kabashima, Shigenori
Fukuie, Tatsuki
Ohya, Yukihiro
author_facet Yasudo, Hiroki
Yamamoto-Hanada, Kiwako
Yang, Limin
Saito-Abe, Mayako
Sato, Miori
Miyaji, Yumiko
Shimada, Mami
Hirai, Seiko
Toyokuni, Kenji
Ishikawa, Fumi
Inuzuka, Yusuke
Kabashima, Shigenori
Fukuie, Tatsuki
Ohya, Yukihiro
author_sort Yasudo, Hiroki
collection PubMed
description The association between pollen food allergy syndrome (PFAS) and allergic march remains unclear. In this prospective cohort study of the general population in Tokyo (T-Child Study), we found that sensitization to Cry j 1 and Fel d 1 at ages 5 and 9 years was associated with an increased risk of PFAS at 13 years old (at 5 years, Cry j 1: adjusted odds ratio aOR, 2.74; 95% confidence interval CI, 1.53–4.91; Fel d 1: aOR, 2.61; 95% CI, 1.31–5.19; at 9 years, Cry j 1: adjusted odds ratio aOR, 4.28; 95% confidence interval CI, 1.98–9.25; Fel d 1: aOR, 2.40; 95% CI, 1.33–4.32). In particular, sensitization to Bet v 1 at ages 5 and 9 years was associated with a strong risk of PFAS at the age of 13 years (at 5 years: aOR, 10.6; 95% CI, 2.64–42.5; at 9 years: aOR, 9.1; 95% CI, 4.71–17.6). PFAS risk by age 13 years was increased by any allergic symptom at 5 or 9 years, a combination of wheezing, eczema, and rhinitis, and Bet v 1 sensitization. Our findings suggest that PFAS may be associated with allergic march.
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spelling pubmed-92681362022-07-09 Pollen Food Allergy Syndrome in Allergic March Yasudo, Hiroki Yamamoto-Hanada, Kiwako Yang, Limin Saito-Abe, Mayako Sato, Miori Miyaji, Yumiko Shimada, Mami Hirai, Seiko Toyokuni, Kenji Ishikawa, Fumi Inuzuka, Yusuke Kabashima, Shigenori Fukuie, Tatsuki Ohya, Yukihiro Nutrients Article The association between pollen food allergy syndrome (PFAS) and allergic march remains unclear. In this prospective cohort study of the general population in Tokyo (T-Child Study), we found that sensitization to Cry j 1 and Fel d 1 at ages 5 and 9 years was associated with an increased risk of PFAS at 13 years old (at 5 years, Cry j 1: adjusted odds ratio aOR, 2.74; 95% confidence interval CI, 1.53–4.91; Fel d 1: aOR, 2.61; 95% CI, 1.31–5.19; at 9 years, Cry j 1: adjusted odds ratio aOR, 4.28; 95% confidence interval CI, 1.98–9.25; Fel d 1: aOR, 2.40; 95% CI, 1.33–4.32). In particular, sensitization to Bet v 1 at ages 5 and 9 years was associated with a strong risk of PFAS at the age of 13 years (at 5 years: aOR, 10.6; 95% CI, 2.64–42.5; at 9 years: aOR, 9.1; 95% CI, 4.71–17.6). PFAS risk by age 13 years was increased by any allergic symptom at 5 or 9 years, a combination of wheezing, eczema, and rhinitis, and Bet v 1 sensitization. Our findings suggest that PFAS may be associated with allergic march. MDPI 2022-06-27 /pmc/articles/PMC9268136/ /pubmed/35807837 http://dx.doi.org/10.3390/nu14132658 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yasudo, Hiroki
Yamamoto-Hanada, Kiwako
Yang, Limin
Saito-Abe, Mayako
Sato, Miori
Miyaji, Yumiko
Shimada, Mami
Hirai, Seiko
Toyokuni, Kenji
Ishikawa, Fumi
Inuzuka, Yusuke
Kabashima, Shigenori
Fukuie, Tatsuki
Ohya, Yukihiro
Pollen Food Allergy Syndrome in Allergic March
title Pollen Food Allergy Syndrome in Allergic March
title_full Pollen Food Allergy Syndrome in Allergic March
title_fullStr Pollen Food Allergy Syndrome in Allergic March
title_full_unstemmed Pollen Food Allergy Syndrome in Allergic March
title_short Pollen Food Allergy Syndrome in Allergic March
title_sort pollen food allergy syndrome in allergic march
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268136/
https://www.ncbi.nlm.nih.gov/pubmed/35807837
http://dx.doi.org/10.3390/nu14132658
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