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Pollen Food Allergy Syndrome in Allergic March
The association between pollen food allergy syndrome (PFAS) and allergic march remains unclear. In this prospective cohort study of the general population in Tokyo (T-Child Study), we found that sensitization to Cry j 1 and Fel d 1 at ages 5 and 9 years was associated with an increased risk of PFAS...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268136/ https://www.ncbi.nlm.nih.gov/pubmed/35807837 http://dx.doi.org/10.3390/nu14132658 |
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author | Yasudo, Hiroki Yamamoto-Hanada, Kiwako Yang, Limin Saito-Abe, Mayako Sato, Miori Miyaji, Yumiko Shimada, Mami Hirai, Seiko Toyokuni, Kenji Ishikawa, Fumi Inuzuka, Yusuke Kabashima, Shigenori Fukuie, Tatsuki Ohya, Yukihiro |
author_facet | Yasudo, Hiroki Yamamoto-Hanada, Kiwako Yang, Limin Saito-Abe, Mayako Sato, Miori Miyaji, Yumiko Shimada, Mami Hirai, Seiko Toyokuni, Kenji Ishikawa, Fumi Inuzuka, Yusuke Kabashima, Shigenori Fukuie, Tatsuki Ohya, Yukihiro |
author_sort | Yasudo, Hiroki |
collection | PubMed |
description | The association between pollen food allergy syndrome (PFAS) and allergic march remains unclear. In this prospective cohort study of the general population in Tokyo (T-Child Study), we found that sensitization to Cry j 1 and Fel d 1 at ages 5 and 9 years was associated with an increased risk of PFAS at 13 years old (at 5 years, Cry j 1: adjusted odds ratio aOR, 2.74; 95% confidence interval CI, 1.53–4.91; Fel d 1: aOR, 2.61; 95% CI, 1.31–5.19; at 9 years, Cry j 1: adjusted odds ratio aOR, 4.28; 95% confidence interval CI, 1.98–9.25; Fel d 1: aOR, 2.40; 95% CI, 1.33–4.32). In particular, sensitization to Bet v 1 at ages 5 and 9 years was associated with a strong risk of PFAS at the age of 13 years (at 5 years: aOR, 10.6; 95% CI, 2.64–42.5; at 9 years: aOR, 9.1; 95% CI, 4.71–17.6). PFAS risk by age 13 years was increased by any allergic symptom at 5 or 9 years, a combination of wheezing, eczema, and rhinitis, and Bet v 1 sensitization. Our findings suggest that PFAS may be associated with allergic march. |
format | Online Article Text |
id | pubmed-9268136 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92681362022-07-09 Pollen Food Allergy Syndrome in Allergic March Yasudo, Hiroki Yamamoto-Hanada, Kiwako Yang, Limin Saito-Abe, Mayako Sato, Miori Miyaji, Yumiko Shimada, Mami Hirai, Seiko Toyokuni, Kenji Ishikawa, Fumi Inuzuka, Yusuke Kabashima, Shigenori Fukuie, Tatsuki Ohya, Yukihiro Nutrients Article The association between pollen food allergy syndrome (PFAS) and allergic march remains unclear. In this prospective cohort study of the general population in Tokyo (T-Child Study), we found that sensitization to Cry j 1 and Fel d 1 at ages 5 and 9 years was associated with an increased risk of PFAS at 13 years old (at 5 years, Cry j 1: adjusted odds ratio aOR, 2.74; 95% confidence interval CI, 1.53–4.91; Fel d 1: aOR, 2.61; 95% CI, 1.31–5.19; at 9 years, Cry j 1: adjusted odds ratio aOR, 4.28; 95% confidence interval CI, 1.98–9.25; Fel d 1: aOR, 2.40; 95% CI, 1.33–4.32). In particular, sensitization to Bet v 1 at ages 5 and 9 years was associated with a strong risk of PFAS at the age of 13 years (at 5 years: aOR, 10.6; 95% CI, 2.64–42.5; at 9 years: aOR, 9.1; 95% CI, 4.71–17.6). PFAS risk by age 13 years was increased by any allergic symptom at 5 or 9 years, a combination of wheezing, eczema, and rhinitis, and Bet v 1 sensitization. Our findings suggest that PFAS may be associated with allergic march. MDPI 2022-06-27 /pmc/articles/PMC9268136/ /pubmed/35807837 http://dx.doi.org/10.3390/nu14132658 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Yasudo, Hiroki Yamamoto-Hanada, Kiwako Yang, Limin Saito-Abe, Mayako Sato, Miori Miyaji, Yumiko Shimada, Mami Hirai, Seiko Toyokuni, Kenji Ishikawa, Fumi Inuzuka, Yusuke Kabashima, Shigenori Fukuie, Tatsuki Ohya, Yukihiro Pollen Food Allergy Syndrome in Allergic March |
title | Pollen Food Allergy Syndrome in Allergic March |
title_full | Pollen Food Allergy Syndrome in Allergic March |
title_fullStr | Pollen Food Allergy Syndrome in Allergic March |
title_full_unstemmed | Pollen Food Allergy Syndrome in Allergic March |
title_short | Pollen Food Allergy Syndrome in Allergic March |
title_sort | pollen food allergy syndrome in allergic march |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268136/ https://www.ncbi.nlm.nih.gov/pubmed/35807837 http://dx.doi.org/10.3390/nu14132658 |
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