SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipients

The emergence of SARS-CoV-2 variants harboring mutations in the spike (S) protein has raised concern about potential immune escape. Here, we studied humoral and cellular immune responses to wild-type SARS-CoV-2 and the B.1.1.7 and B.1.351 variants of concern in a cohort of 121 BNT162b2 messenger RNA...

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Detalles Bibliográficos
Autores principales: Geers, Daryl, Shamier, Marc C., Bogers, Susanne, den Hartog, Gerco, Gommers, Lennert, Nieuwkoop, Nella N., Schmitz, Katharina S., Rijsbergen, Laurine C., van Osch, Jolieke A. T., Dijkhuizen, Emma, Smits, Gaby, Comvalius, Anouskha, van Mourik, Djenolan, Caniels, Tom G., van Gils, Marit J., Sanders, Rogier W., Oude Munnink, Bas B., Molenkamp, Richard, de Jager, Herbert J., Haagmans, Bart L., de Swart, Rik L., Koopmans, Marion P. G., van Binnendijk, Robert S., de Vries, Rory D., GeurtsvanKessel, Corine H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268159/
https://www.ncbi.nlm.nih.gov/pubmed/34035118
http://dx.doi.org/10.1126/sciimmunol.abj1750

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