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Conversion of Natural Narciclasine to Its C-1 and C-6 Derivatives and Their Antitumor Activity Evaluation: Some Unusual Chemistry of Narciclasine †

During the search for a general, efficient route toward the synthesis of C-1 analogues of narciclasine, natural narciclasine was protected and converted to its C-1 enol derivative using a novel semi-synthetic route. Attempted conversion of this material to its triflate in order to conduct cross-coup...

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Detalles Bibliográficos
Autores principales: Goulart Stollmaier, Juana, Thomson, Jared, Endoma-Arias, Mary Ann, Simionescu, Razvan, Vernaza, Alexandra, Mesa-Diaz, Nakya, Smith, Mitchell, Du, Liqin, Kornienko, Alexander, Hudlicky, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268329/
https://www.ncbi.nlm.nih.gov/pubmed/35807391
http://dx.doi.org/10.3390/molecules27134141