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Advanced Development of Supercritical Fluid Chromatography in Herbal Medicine Analysis

The greatest challenge in the analysis of herbal components lies in their variety and complexity. Therefore, efficient analytical tools for the separation and qualitative and quantitative analysis of multi-components are essential. In recent years, various emerging analytical techniques have offered...

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Detalles Bibliográficos
Autores principales: Chen, Min, Wen, Shan-Shan, Wang, Rui, Ren, Qing-Xuan, Guo, Chen-Wan, Li, Ping, Gao, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268462/
https://www.ncbi.nlm.nih.gov/pubmed/35807405
http://dx.doi.org/10.3390/molecules27134159
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author Chen, Min
Wen, Shan-Shan
Wang, Rui
Ren, Qing-Xuan
Guo, Chen-Wan
Li, Ping
Gao, Wen
author_facet Chen, Min
Wen, Shan-Shan
Wang, Rui
Ren, Qing-Xuan
Guo, Chen-Wan
Li, Ping
Gao, Wen
author_sort Chen, Min
collection PubMed
description The greatest challenge in the analysis of herbal components lies in their variety and complexity. Therefore, efficient analytical tools for the separation and qualitative and quantitative analysis of multi-components are essential. In recent years, various emerging analytical techniques have offered significant support for complicated component analysis, with breakthroughs in selectivity, sensitivity, and rapid analysis. Among these techniques, supercritical fluid chromatography (SFC) has attracted much attention because of its high column efficiency and environmental protection. SFC can be used to analyze a wide range of compounds, including non-polar and polar compounds, making it a prominent analytical platform. The applicability of SFC for the separation and determination of natural products in herbal medicines is overviewed in this article. The range of applications was expanded through the selection and optimization of stationary phases and mobile phases. We also focus on the two-dimensional SFC analysis. This paper provides new insight into SFC method development for herbal medicine analysis.
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spelling pubmed-92684622022-07-09 Advanced Development of Supercritical Fluid Chromatography in Herbal Medicine Analysis Chen, Min Wen, Shan-Shan Wang, Rui Ren, Qing-Xuan Guo, Chen-Wan Li, Ping Gao, Wen Molecules Review The greatest challenge in the analysis of herbal components lies in their variety and complexity. Therefore, efficient analytical tools for the separation and qualitative and quantitative analysis of multi-components are essential. In recent years, various emerging analytical techniques have offered significant support for complicated component analysis, with breakthroughs in selectivity, sensitivity, and rapid analysis. Among these techniques, supercritical fluid chromatography (SFC) has attracted much attention because of its high column efficiency and environmental protection. SFC can be used to analyze a wide range of compounds, including non-polar and polar compounds, making it a prominent analytical platform. The applicability of SFC for the separation and determination of natural products in herbal medicines is overviewed in this article. The range of applications was expanded through the selection and optimization of stationary phases and mobile phases. We also focus on the two-dimensional SFC analysis. This paper provides new insight into SFC method development for herbal medicine analysis. MDPI 2022-06-29 /pmc/articles/PMC9268462/ /pubmed/35807405 http://dx.doi.org/10.3390/molecules27134159 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chen, Min
Wen, Shan-Shan
Wang, Rui
Ren, Qing-Xuan
Guo, Chen-Wan
Li, Ping
Gao, Wen
Advanced Development of Supercritical Fluid Chromatography in Herbal Medicine Analysis
title Advanced Development of Supercritical Fluid Chromatography in Herbal Medicine Analysis
title_full Advanced Development of Supercritical Fluid Chromatography in Herbal Medicine Analysis
title_fullStr Advanced Development of Supercritical Fluid Chromatography in Herbal Medicine Analysis
title_full_unstemmed Advanced Development of Supercritical Fluid Chromatography in Herbal Medicine Analysis
title_short Advanced Development of Supercritical Fluid Chromatography in Herbal Medicine Analysis
title_sort advanced development of supercritical fluid chromatography in herbal medicine analysis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268462/
https://www.ncbi.nlm.nih.gov/pubmed/35807405
http://dx.doi.org/10.3390/molecules27134159
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