Vitamin D Treatment Prevents Uremia-Induced Reductions in Aortic microRNA-145 Attenuating Osteogenic Differentiation despite Hyperphosphatemia

In chronic kidney disease, systemic inflammation and high serum phosphate (P) promote the de-differentiation of vascular smooth muscle cells (VSMC) to osteoblast-like cells, increasing the propensity for medial calcification and cardiovascular mortality. Vascular microRNA-145 (miR-145) content is es...

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Detalles Bibliográficos
Autores principales: Carrillo-López, Natalia, Panizo, Sara, Arcidiacono, Maria Vittoria, de la Fuente, Sandra, Martínez-Arias, Laura, Ottaviano, Emerenziana, Ulloa, Catalina, Ruiz-Torres, María Piedad, Rodríguez, Isabel, Cannata-Andía, Jorge B., Naves-Díaz, Manuel, Dusso, Adriana S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268464/
https://www.ncbi.nlm.nih.gov/pubmed/35807767
http://dx.doi.org/10.3390/nu14132589

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