Cargando…

The Assessment of Meloxicam Phototoxicity in Human Normal Skin Cells: In Vitro Studies on Dermal Fibroblasts and Epidermal Melanocytes

Meloxicam (MLX), which belongs to the oxicam nonsteroidal anti-inflammatory drug derivatives, is an inhibitor of the cyclooxygenase-2 (COX-2) enzyme. Cutaneous adverse effects caused by interaction between UVA radiation and exogenous factors can manifest as phototoxic reactions. Phototoxicity may be...

Descripción completa

Detalles Bibliográficos
Autores principales:	Karkoszka, Marta, Rok, Jakub, Banach, Klaudia, Kowalska, Justyna, Rzepka, Zuzanna, Wrześniok, Dorota
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268563/ https://www.ncbi.nlm.nih.gov/pubmed/35807460 http://dx.doi.org/10.3390/molecules27134215

Ejemplares similares

Changes in the Oxidation-Reduction State of Human Dermal Fibroblasts as an Effect of Lomefloxacin Phototoxic Action
por: Kowalska, Justyna, et al.
Publicado: (2022)

Molecular and Biochemical Basis of Fluoroquinolones-Induced Phototoxicity—The Study of Antioxidant System in Human Melanocytes Exposed to UV-A Radiation
por: Kowalska, Justyna, et al.
Publicado: (2020)

The Assessment of the Phototoxic Action of Chlortetracycline and Doxycycline as a Potential Treatment of Melanotic Melanoma—Biochemical and Molecular Studies on COLO 829 and G-361 Cell Lines
por: Rok, Jakub, et al.
Publicado: (2023)

Molecular and Biochemical Basis of Minocycline-Induced Hyperpigmentation—The Study on Normal Human Melanocytes Exposed to UVA and UVB Radiation
por: Rok, Jakub, et al.
Publicado: (2021)

The Biochemical and Molecular Analysis of Changes in Melanogenesis Induced by UVA-Activated Fluoroquinolones—In Vitro Study on Human Normal Melanocytes
por: Kowalska, Justyna, et al.
Publicado: (2021)

Ketoprofen Combined with UVA Irradiation Exerts Higher Selectivity in the Mode of Action against Melanotic Melanoma Cells than against Normal Human Melanocytes
por: Banach, Klaudia, et al.
Publicado: (2021)

Cobalamin Deficiency May Induce Astrosenescence—An In Vitro Study
por: Rzepka, Zuzanna, et al.
Publicado: (2022)

The Anticancer Potential of Doxycycline and Minocycline—A Comparative Study on Amelanotic Melanoma Cell Lines
por: Rok, Jakub, et al.
Publicado: (2022)

Chemosensitization of U-87 MG Glioblastoma Cells by Neobavaisoflavone towards Doxorubicin and Etoposide
por: Maszczyk, Mateusz, et al.
Publicado: (2022)

The Assessment of Anti-Melanoma Potential of Tigecycline—Cellular and Molecular Studies of Cell Proliferation, Apoptosis and Autophagy on Amelanotic and Melanotic Melanoma Cells
por: Rok, Jakub, et al.
Publicado: (2023)

Minocycline Impact on Redox Homeostasis of Normal Human Melanocytes HEMn-LP Exposed to UVA Radiation and Hydrogen Peroxide
por: Rok, Jakub, et al.
Publicado: (2021)

Drug-Induced Photosensitivity—From Light and Chemistry to Biological Reactions and Clinical Symptoms
por: Kowalska, Justyna, et al.
Publicado: (2021)

Astrogliosis in an Experimental Model of Hypovitaminosis B12: A Cellular Basis of Neurological Disorders Due to Cobalamin Deficiency
por: Rzepka, Zuzanna, et al.
Publicado: (2020)

UVA Radiation Enhances Lomefloxacin-Mediated Cytotoxic, Growth-Inhibitory and Pro-Apoptotic Effect in Human Melanoma Cells through Excessive Reactive Oxygen Species Generation
por: Beberok, Artur, et al.
Publicado: (2020)

Evaluation of Possible Neobavaisoflavone Chemosensitizing Properties towards Doxorubicin and Etoposide in SW1783 Anaplastic Astrocytoma Cells
por: Maszczyk, Mateusz, et al.
Publicado: (2023)

Vitamin B(12) Deficiency Induces Imbalance in Melanocytes Homeostasis—A Cellular Basis of Hypocobalaminemia Pigmentary Manifestations
por: Rzepka, Zuzanna, et al.
Publicado: (2018)

Cellular and Molecular Aspects of Anti-Melanoma Effect of Minocycline—A Study of Cytotoxicity and Apoptosis on Human Melanotic Melanoma Cells
por: Rok, Jakub, et al.
Publicado: (2020)

Cobalamin Deficiency: Effect on Homeostasis of Cultured Human Astrocytes
por: Rzepka, Zuzanna, et al.
Publicado: (2019)

Effect of norfloxacin and moxifloxacin on melanin synthesis and antioxidant enzymes activity in normal human melanocytes
por: Beberok, Artur, et al.
Publicado: (2014)

EPR spectroscopy of chlorpromazine-induced free radical formation in normal human melanocytes
por: Otręba, Michał, et al.
Publicado: (2015)

Mcl-1 Inhibitor Induces Cells Death in BRAF-Mutant Amelanotic Melanoma Trough GSH Depletion, DNA Damage and Cell Cycle Changes
por: Respondek, Michalina, et al.
Publicado: (2019)

Neobavaisoflavone May Modulate the Activity of Topoisomerase Inhibitors towards U-87 MG Cells: An In Vitro Study
por: Maszczyk, Mateusz, et al.
Publicado: (2021)

Effect of thioridazine on antioxidant status of HEMn-DP melanocytes
por: Otręba, Michał, et al.
Publicado: (2015)

Response of Human Glioblastoma Cells to Vitamin B12 Deficiency: A Study Using the Non-Toxic Cobalamin Antagonist
por: Rzepka, Zuzanna, et al.
Publicado: (2021)

Interaction between moxifloxacin and Mcl-1 and MITF proteins: the effect on growth inhibition and apoptosis in MDA-MB-231 human triple-negative breast cancer cells
por: Beberok, Artur, et al.
Publicado: (2022)

Nicotine impact on melanogenesis and antioxidant defense system in HEMn-DP melanocytes
por: Delijewski, Marcin, et al.
Publicado: (2014)

Lomefloxacin Induces Oxidative Stress and Apoptosis in COLO829 Melanoma Cells
por: Beberok, Artur, et al.
Publicado: (2017)

Two Cases of Vitiligo Developed on the Persisting Dermal Melanocytosis: Is There a Difference between Epidermal Melanocytes and Dermal Melanocytes?
por: Ahn, Jae-Jun, et al.
Publicado: (2013)

In vitro melanogenesis inhibition by fluphenazine and prochlorperazine in normal human melanocytes lightly pigmented
por: Otręba, Michał, et al.
Publicado: (2018)

New Betulin Derivatives with Nitrogen Heterocyclic Moiety—Synthesis and Anticancer Activity In Vitro
por: Bębenek, Ewa, et al.
Publicado: (2022)

Synthesis and Anticancer Activity of Indole-Functionalized Derivatives of Betulin
por: Rzepka, Zuzanna, et al.
Publicado: (2022)

Role of the Skin Microenvironment in Melanomagenesis: Epidermal Keratinocytes and Dermal Fibroblasts Promote BRAF Oncogene-Induced Senescence Escape in Melanocytes
por: Sadangi, Shreyans, et al.
Publicado: (2022)

Targeting senescent dermal fibroblasts responsible for hyperactive melanocytes in melasma
por: Wan, Jing, et al.
Publicado: (2023)

Deformable Liposomal Hydrogel for Dermal and Transdermal Delivery of Meloxicam
por: Zhang, Zhang Julia, et al.
Publicado: (2020)

Vandetanib induced phototoxic reaction progressed to toxic epidermal necrolysis()
por: Gul, Busra Demirbag, et al.
Publicado: (2022)

Race Does Not Predict Melanocyte Heterogeneous Responses to Dermal Fibroblast-Derived Mediators
por: Sirimahachaiyakul, Pornthep, et al.
Publicado: (2015)

Dermal Fibroblasts Internalize Phosphatidylserine-Exposed Secretory Melanosome Clusters and Apoptotic Melanocytes
por: Ando, Hideya, et al.
Publicado: (2020)

Design, Synthesis and Biological Evaluation of Quinoline-8-Sulfonamides as Inhibitors of the Tumor Cell-Specific M2 Isoform of Pyruvate Kinase: Preliminary Study
por: Marciniec, Krzysztof, et al.
Publicado: (2023)

Paraganglioma-Like Dermal Melanocytic Tumor
por: Thyvalappil, Anoop, et al.
Publicado: (2015)

Phototoxic or Photoprotective?—Advances and Limitations of Titanium (IV) Oxide in Dermal Formulations—A Review
por: Gackowski, Michał, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ghe2p2f9q10b2tcrrsp9ok9e74