Cargando…

Thymoquinone Produces Cardioprotective Effect in β-Receptor Stimulated Myocardial Infarcted Rats via Subsiding Oxidative Stress and Inflammation

Earlier studies reported that long-term treatment with thymoquinone (TQ) at a high dose (20 mg/kg) exerts a cardioprotective effect against isoproterenol (ISO)-triggered myocardial infarction (MI) in rats. In the present study, we tested the hypothesis that TQ, as a potent molecule, can exhibit card...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rathod, Sumit, Agrawal, Yogeeta, Sherikar, Abdulla, Nakhate, Kartik T., Patil, Chandragouda R., Nagoor Meeran, M. F., Ojha, Shreesh, Goyal, Sameer N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268596/ https://www.ncbi.nlm.nih.gov/pubmed/35807920 http://dx.doi.org/10.3390/nu14132742

Ejemplares similares

Neuroinflammation in the Central Nervous System: Exploring the Evolving Influence of Endocannabinoid System
por: Rathod, Sumit S., et al.
Publicado: (2023)

Curcumin Protects Diabetic Mice against Isoproterenol-Induced Myocardial Infarction by Modulating CB2 Cannabinoid Receptors
por: Pawar, Harshal D., et al.
Publicado: (2022)

Ghrelin mediated regulation of neurosynaptic transmitters in depressive disorders
por: Masule, Milind V., et al.
Publicado: (2022)

In vitro and in vivo characterization of Entacapone-loaded nanostructured lipid carriers developed by quality-by-design approach
por: Agrawal, Yogeeta, et al.
Publicado: (2022)

Pharmacological Properties, Molecular Mechanisms, and Pharmaceutical Development of Asiatic Acid: A Pentacyclic Triterpenoid of Therapeutic Promise
por: Nagoor Meeran, Mohamed Fizur, et al.
Publicado: (2018)

Therapeutic Potential of Plants and Plant Derived Phytochemicals against Acetaminophen-Induced Liver Injury
por: Subramanya, Sandeep B., et al.
Publicado: (2018)

Serratiopeptidase, A Serine Protease Anti-Inflammatory, Fibrinolytic, and Mucolytic Drug, Can Be a Useful Adjuvant for Management in COVID-19
por: Sharma, Charu, et al.
Publicado: (2021)

Protective Effects of Cardamom in Isoproterenol-Induced Myocardial Infarction in Rats
por: Goyal, Sameer N., et al.
Publicado: (2015)

Therapeutic Potential and Pharmaceutical Development of a Multitargeted Flavonoid Phloretin
por: Nakhate, Kartik T., et al.
Publicado: (2022)

Hesperidin Produces Cardioprotective Activity via PPAR-γ Pathway in Ischemic Heart Disease Model in Diabetic Rats
por: Agrawal, Yogeeta O., et al.
Publicado: (2014)

Carboxymethylated Gums and Derivatization: Strategies and Significance in Drug Delivery and Tissue Engineering
por: Baghel, Madhuri, et al.
Publicado: (2023)

Therapeutic Potential and Pharmaceutical Development of Thymoquinone: A Multitargeted Molecule of Natural Origin
por: Goyal, Sameer N., et al.
Publicado: (2017)

Past and current perspective on new therapeutic targets for Type-II diabetes
por: Patil, Pradip D, et al.
Publicado: (2017)

Protective Effect of Thymoquinone against Cyclophosphamide-Induced Hemorrhagic Cystitis through Inhibiting DNA Damage and Upregulation of Nrf2 Expression
por: Gore, Prashant R., et al.
Publicado: (2016)

β-Caryophyllene, A Natural Dietary CB2 Receptor Selective Cannabinoid can be a Candidate to Target the Trinity of Infection, Immunity, and Inflammation in COVID-19
por: Jha, Niraj Kumar, et al.
Publicado: (2021)

The Protective Effect of Apigenin on Myocardial Injury in Diabetic Rats mediating Activation of the PPAR-γ Pathway
por: Mahajan, Umesh B., et al.
Publicado: (2017)

Ezetimibe-Loaded Nanostructured Lipid Carrier Based Formulation Ameliorates Hyperlipidaemia in an Experimental Model of High Fat Diet
por: Agrawal, Yogeeta O., et al.
Publicado: (2021)

An Update on Advancements and Challenges in Inhalational Drug Delivery for Pulmonary Arterial Hypertension
por: Agnihotri, Vinit, et al.
Publicado: (2022)

Nerolidol Attenuates Oxidative Stress, Inflammation, and Apoptosis by Modulating Nrf2/MAPK Signaling Pathways in Doxorubicin-Induced Acute Cardiotoxicity in Rats
por: Arunachalam, Seenipandi, et al.
Publicado: (2021)

Can Echinacea be a potential candidate to target immunity, inflammation, and infection - The trinity of coronavirus disease 2019
por: Nagoor Meeran, M.F., et al.
Publicado: (2021)

Cardioprotective Potentials of Plant-Derived Small Molecules against Doxorubicin Associated Cardiotoxicity
por: Ojha, Shreesh, et al.
Publicado: (2016)

Recent Advancements in Topical Anti-Psoriatic Nanostructured Lipid Carrier-Based Drug Delivery
por: Patil, Tulshidas S., et al.
Publicado: (2023)

Carvacrol, a Plant Metabolite Targeting Viral Protease (M(pro)) and ACE2 in Host Cells Can Be a Possible Candidate for COVID-19
por: Javed, Hayate, et al.
Publicado: (2021)

Nootkatone, a Dietary Fragrant Bioactive Compound, Attenuates Dyslipidemia and Intramyocardial Lipid Accumulation and Favorably Alters Lipid Metabolism in a Rat Model of Myocardial Injury: An In Vivo and In Vitro Study
por: Meeran, M.F. Nagoor, et al.
Publicado: (2020)

Can limonene be a possible candidate for evaluation as an agent or adjuvant against infection, immunity, and inflammation in COVID-19?
por: Nagoor Meeran, M.F., et al.
Publicado: (2020)

Pentacyclic Triterpenoids Inhibit IKKβ Mediated Activation of NF-κB Pathway: In Silico and In Vitro Evidences
por: Patil, Kalpesh R., et al.
Publicado: (2015)

Neuroprotective Effects of Thymol, a Dietary Monoterpene Against Dopaminergic Neurodegeneration in Rotenone-Induced Rat Model of Parkinson’s Disease
por: Javed, Hayate, et al.
Publicado: (2019)

Animal Models of Inflammation for Screening of Anti-inflammatory Drugs: Implications for the Discovery and Development of Phytopharmaceuticals
por: Patil, Kalpesh R., et al.
Publicado: (2019)

Methotrexate-Loaded Nanostructured Lipid Carrier Gel Alleviates Imiquimod-Induced Psoriasis by Moderating Inflammation: Formulation, Optimization, Characterization, In-Vitro and In-Vivo Studies
por: Agrawal, Yogeeta O, et al.
Publicado: (2020)

Pharmacological Properties and Molecular Mechanisms of Thymol: Prospects for Its Therapeutic Potential and Pharmaceutical Development
por: Nagoor Meeran, Mohamed Fizur, et al.
Publicado: (2017)

Neuroprotective Potential and Underlying Pharmacological Mechanism of Carvacrol for Alzheimer’s and Parkinson’s Diseases
por: Javed, Hayate, et al.
Publicado: (2023)

Tannic Acid Mitigates Rotenone-Induced Dopaminergic Neurodegeneration by Inhibiting Inflammation, Oxidative Stress, Apoptosis, and Glutamate Toxicity in Rats
por: Azimullah, Sheikh, et al.
Publicado: (2023)

In vivo and in vitro protective effects of omeprazole against neuropathic pain
por: Chanchal, Sanjay K., et al.
Publicado: (2016)

Chemomodulatory Potential of Bartogenic Acid Against DMBA/Croton Oil Induced Two-Step Skin Carcinogenesis in Mice
por: Patil, Chandragouda R., et al.
Publicado: (2016)

Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of α-Bisabolol
por: Eddin, Lujain Bader, et al.
Publicado: (2022)

Plant Extracts and Phytochemicals Targeting α-Synuclein Aggregation in Parkinson's Disease Models
por: Javed, Hayate, et al.
Publicado: (2019)

Limonene, a Monoterpene, Mitigates Rotenone-Induced Dopaminergic Neurodegeneration by Modulating Neuroinflammation, Hippo Signaling and Apoptosis in Rats
por: Eddin, Lujain Bader, et al.
Publicado: (2023)

Therapeutic Potential of β-Caryophyllene: A Dietary Cannabinoid in Diabetes and Associated Complications
por: Hashiesh, Hebaallah Mamdouh, et al.
Publicado: (2020)

Neuroprotective Potential of Limonene and Limonene Containing Natural Products
por: Eddin, Lujain Bader, et al.
Publicado: (2021)

RETRACTED ARTICLE: Ultra-diluted Toxicodendron pubescens attenuates pro-inflammatory cytokines and ROS- mediated neuropathic pain in rats
por: Magar, Shital, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_06clru9v8icrt7i6ptasn4oh50