Discovery of Phenylcarbamoylazinane-1,2,4-Triazole Amides Derivatives as the Potential Inhibitors of Aldo-Keto Reductases (AKR1B1 & AKRB10): Potential Lead Molecules for Treatment of Colon Cancer

Both members of the aldo-keto reductases (AKRs) family, AKR1B1 and AKR1B10, are over-expressed in various type of cancer, making them potential targets for inflammation-mediated cancers such as colon, lung, breast, and prostate cancers. This is the first comprehensive study which focused on the iden...

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Detalles Bibliográficos
Autores principales: Saeed, Amna, Ejaz, Syeda Abida, Sarfraz, Muhammad, Tamam, Nissren, Siddique, Farhan, Riaz, Naheed, Qais, Faizan Abul, Chtita, Samir, Iqbal, Jamshed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268700/
https://www.ncbi.nlm.nih.gov/pubmed/35807227
http://dx.doi.org/10.3390/molecules27133981

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