Nutrition and Immunity in Perinatal Hypoxic-Ischemic Injury

Perinatal hypoxia ischaemia (PHI), acute and chronic, may be associated with considerable adverse outcomes in the foetus and neonate. The molecular and cellular mechanisms of injury and repair associated with PHI in the perinate are not completely understood. Increasing evidence is mounting for the...

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Autores principales: Gandecha, Hema, Kaur, Avineet, Sanghera, Ranveer, Preece, Joanna, Pillay, Thillagavathie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269416/
https://www.ncbi.nlm.nih.gov/pubmed/35807927
http://dx.doi.org/10.3390/nu14132747
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author Gandecha, Hema
Kaur, Avineet
Sanghera, Ranveer
Preece, Joanna
Pillay, Thillagavathie
author_facet Gandecha, Hema
Kaur, Avineet
Sanghera, Ranveer
Preece, Joanna
Pillay, Thillagavathie
author_sort Gandecha, Hema
collection PubMed
description Perinatal hypoxia ischaemia (PHI), acute and chronic, may be associated with considerable adverse outcomes in the foetus and neonate. The molecular and cellular mechanisms of injury and repair associated with PHI in the perinate are not completely understood. Increasing evidence is mounting for the role of nutrients and bioactive food components in immune development, function and repair in PHI. In this review, we explore current concepts around the neonatal immune response to PHI with a specific emphasis on the impact of nutrition in the mother, foetus and neonate.
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spelling pubmed-92694162022-07-09 Nutrition and Immunity in Perinatal Hypoxic-Ischemic Injury Gandecha, Hema Kaur, Avineet Sanghera, Ranveer Preece, Joanna Pillay, Thillagavathie Nutrients Review Perinatal hypoxia ischaemia (PHI), acute and chronic, may be associated with considerable adverse outcomes in the foetus and neonate. The molecular and cellular mechanisms of injury and repair associated with PHI in the perinate are not completely understood. Increasing evidence is mounting for the role of nutrients and bioactive food components in immune development, function and repair in PHI. In this review, we explore current concepts around the neonatal immune response to PHI with a specific emphasis on the impact of nutrition in the mother, foetus and neonate. MDPI 2022-07-01 /pmc/articles/PMC9269416/ /pubmed/35807927 http://dx.doi.org/10.3390/nu14132747 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Gandecha, Hema
Kaur, Avineet
Sanghera, Ranveer
Preece, Joanna
Pillay, Thillagavathie
Nutrition and Immunity in Perinatal Hypoxic-Ischemic Injury
title Nutrition and Immunity in Perinatal Hypoxic-Ischemic Injury
title_full Nutrition and Immunity in Perinatal Hypoxic-Ischemic Injury
title_fullStr Nutrition and Immunity in Perinatal Hypoxic-Ischemic Injury
title_full_unstemmed Nutrition and Immunity in Perinatal Hypoxic-Ischemic Injury
title_short Nutrition and Immunity in Perinatal Hypoxic-Ischemic Injury
title_sort nutrition and immunity in perinatal hypoxic-ischemic injury
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269416/
https://www.ncbi.nlm.nih.gov/pubmed/35807927
http://dx.doi.org/10.3390/nu14132747
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