Development and application of a next-generation sequencing protocol and bioinformatics pipeline for the comprehensive analysis of the canine immunoglobulin repertoire

Profiling the adaptive immune repertoire using next generation sequencing (NGS) has become common in human medicine, showing promise in characterizing clonal expansion of B cell clones through analysis of B cell receptors (BCRs) in patients with lymphoid malignancies. In contrast, most work evaluati...

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Detalles Bibliográficos
Autores principales: Cullen, Jonah N., Martin, Jolyon, Vilella, Albert J., Treeful, Amy, Sargan, David, Bradley, Allan, Friedenberg, Steven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269486/
https://www.ncbi.nlm.nih.gov/pubmed/35802654
http://dx.doi.org/10.1371/journal.pone.0270710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269486/
https://www.ncbi.nlm.nih.gov/pubmed/35802654
http://dx.doi.org/10.1371/journal.pone.0270710

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