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Pixel Image Analysis and Its Application with an Alcohol-Based Liquid Scintillator for Particle Therapy

We synthesized an alcohol-based liquid scintillator (AbLS), and we implemented an auxiliary monitoring system with short calibration intervals using AbLS for particle therapy. The commercial liquid scintillator used in previous studies did not allow the user to control the chemical ratio and its com...

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Autores principales: Choi, Ji-Won, Choi, Ji-Young, Jang, Hanil, Joo, Kyung-Kwang, Kim, Byoung-Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269500/
https://www.ncbi.nlm.nih.gov/pubmed/35808370
http://dx.doi.org/10.3390/s22134876
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author Choi, Ji-Won
Choi, Ji-Young
Jang, Hanil
Joo, Kyung-Kwang
Kim, Byoung-Chan
author_facet Choi, Ji-Won
Choi, Ji-Young
Jang, Hanil
Joo, Kyung-Kwang
Kim, Byoung-Chan
author_sort Choi, Ji-Won
collection PubMed
description We synthesized an alcohol-based liquid scintillator (AbLS), and we implemented an auxiliary monitoring system with short calibration intervals using AbLS for particle therapy. The commercial liquid scintillator used in previous studies did not allow the user to control the chemical ratio and its composition. In our study, the chemical ratio of AbLS was freely controlled by simultaneously mixing water and alcohol. To make an equivalent substance to the human body, 2-ethoxyethanol was used. There was no significant difference between AbLS and water in areal density. As an application of AbLS, the range was measured with AbLS using an electron beam in an image analysis that combined AbLS and a digital phone camera. Given a range–energy relationship for the electron expressed as areal density, the electron beam range (cm) in water can be easily estimated. To date, no literature report for the direct comparison of a pixel image analysis and Monte Carlo (MC) simulation has been published. Furthermore, optical tomography of the inverse problem was performed with AbLS and a mobile phone camera. Analyses of optical tomography images provide deeper insight into Radon transformation. In addition, the human phantom, which is difficult to compose with semiconductor diodes, was easily implemented as an image acquisition and analysis system.
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spelling pubmed-92695002022-07-09 Pixel Image Analysis and Its Application with an Alcohol-Based Liquid Scintillator for Particle Therapy Choi, Ji-Won Choi, Ji-Young Jang, Hanil Joo, Kyung-Kwang Kim, Byoung-Chan Sensors (Basel) Article We synthesized an alcohol-based liquid scintillator (AbLS), and we implemented an auxiliary monitoring system with short calibration intervals using AbLS for particle therapy. The commercial liquid scintillator used in previous studies did not allow the user to control the chemical ratio and its composition. In our study, the chemical ratio of AbLS was freely controlled by simultaneously mixing water and alcohol. To make an equivalent substance to the human body, 2-ethoxyethanol was used. There was no significant difference between AbLS and water in areal density. As an application of AbLS, the range was measured with AbLS using an electron beam in an image analysis that combined AbLS and a digital phone camera. Given a range–energy relationship for the electron expressed as areal density, the electron beam range (cm) in water can be easily estimated. To date, no literature report for the direct comparison of a pixel image analysis and Monte Carlo (MC) simulation has been published. Furthermore, optical tomography of the inverse problem was performed with AbLS and a mobile phone camera. Analyses of optical tomography images provide deeper insight into Radon transformation. In addition, the human phantom, which is difficult to compose with semiconductor diodes, was easily implemented as an image acquisition and analysis system. MDPI 2022-06-28 /pmc/articles/PMC9269500/ /pubmed/35808370 http://dx.doi.org/10.3390/s22134876 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Choi, Ji-Won
Choi, Ji-Young
Jang, Hanil
Joo, Kyung-Kwang
Kim, Byoung-Chan
Pixel Image Analysis and Its Application with an Alcohol-Based Liquid Scintillator for Particle Therapy
title Pixel Image Analysis and Its Application with an Alcohol-Based Liquid Scintillator for Particle Therapy
title_full Pixel Image Analysis and Its Application with an Alcohol-Based Liquid Scintillator for Particle Therapy
title_fullStr Pixel Image Analysis and Its Application with an Alcohol-Based Liquid Scintillator for Particle Therapy
title_full_unstemmed Pixel Image Analysis and Its Application with an Alcohol-Based Liquid Scintillator for Particle Therapy
title_short Pixel Image Analysis and Its Application with an Alcohol-Based Liquid Scintillator for Particle Therapy
title_sort pixel image analysis and its application with an alcohol-based liquid scintillator for particle therapy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269500/
https://www.ncbi.nlm.nih.gov/pubmed/35808370
http://dx.doi.org/10.3390/s22134876
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