A phospho-tyrosine–based signaling module using SPOP, CSK, and LYN controls TLR-induced IRF activity

Toll-like receptors (TLRs) recognize pathogen- and host-derived factors and control immune responses via the adaptor protein MyD88 and members of the interferon regulatory transcription factor (IRF) family. IRFs orchestrate key effector functions, including cytokine release, cell differentiation, an...

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Detalles Bibliográficos
Autores principales: Tawaratsumida, Kazuki, Redecke, Vanessa, Wu, Ruiqiong, Kuriakose, Jeeba, Bouchard, Jill J., Mittag, Tanja, Lohman, Brian K., Mishra, Ashutosh, High, Anthony A., Häcker, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269885/
https://www.ncbi.nlm.nih.gov/pubmed/35857476
http://dx.doi.org/10.1126/sciadv.abq0084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269885/
https://www.ncbi.nlm.nih.gov/pubmed/35857476
http://dx.doi.org/10.1126/sciadv.abq0084

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