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Phenotypic and genotypic characterisation of thymine auxotrophy in Escherichia coli isolated from a patient with recurrent bloodstream infection

INTRODUCTION: Thymine auxotrophic in vitro mutants of Escherichia coli were first reported in the mid-20th century. Later, thymine-dependent clinical strains of E. coli as well as other Enterobacterales, Enterococcus faecalis and Staphylococcus aureus have been recognized as the cause of persistent...

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Detalles Bibliográficos
Autores principales: Jakovljev, Aleksandra, Afset, Jan Egil, Haugum, Kjersti, Steinum, Harald Otto, Gresdal Rønning, Torunn, Samuelsen, Ørjan, Ås, Christina Gabrielsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269972/
https://www.ncbi.nlm.nih.gov/pubmed/35802671
http://dx.doi.org/10.1371/journal.pone.0270256