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Thymoma (World Health Organization Type AB) in multiple endocrine neoplasia type 1: a case report

Thymic neoplasms are rarely seen among patients with multiple endocrine neoplasia type 1 (MEN1) and appear to be especially rare when pathological examination reveals a World Health Organization Type AB thymoma. In the case presented here, we report a 39-year-old woman with Type AB thymoma in MEN1....

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Detalles Bibliográficos
Autores principales: Fan, Zheyuan, Wang, Ling, Wang, Jin, Gu, Chundong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270031/
https://www.ncbi.nlm.nih.gov/pubmed/35821790
http://dx.doi.org/10.1093/jscr/rjac290
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author Fan, Zheyuan
Wang, Ling
Wang, Jin
Gu, Chundong
author_facet Fan, Zheyuan
Wang, Ling
Wang, Jin
Gu, Chundong
author_sort Fan, Zheyuan
collection PubMed
description Thymic neoplasms are rarely seen among patients with multiple endocrine neoplasia type 1 (MEN1) and appear to be especially rare when pathological examination reveals a World Health Organization Type AB thymoma. In the case presented here, we report a 39-year-old woman with Type AB thymoma in MEN1. A 7.8-cm-sized mediastinal mass was diagnosed as a thymic neoplasm by computed tomography. In addition, pituitary tumor and hypercalcemia from parathyroid hyperplasia were found. Therefore, the patient was clinically diagnosed with MEN1 syndrome and underwent surgical resection of thymic tumor. At the 1-year follow-up, the patient appeared to be healthy without any sign of reoccurrence. Despite its rare occurrence, our case provides us with a new awareness that thymoma may coexist with MEN1.
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spelling pubmed-92700312022-07-11 Thymoma (World Health Organization Type AB) in multiple endocrine neoplasia type 1: a case report Fan, Zheyuan Wang, Ling Wang, Jin Gu, Chundong J Surg Case Rep Case Report Thymic neoplasms are rarely seen among patients with multiple endocrine neoplasia type 1 (MEN1) and appear to be especially rare when pathological examination reveals a World Health Organization Type AB thymoma. In the case presented here, we report a 39-year-old woman with Type AB thymoma in MEN1. A 7.8-cm-sized mediastinal mass was diagnosed as a thymic neoplasm by computed tomography. In addition, pituitary tumor and hypercalcemia from parathyroid hyperplasia were found. Therefore, the patient was clinically diagnosed with MEN1 syndrome and underwent surgical resection of thymic tumor. At the 1-year follow-up, the patient appeared to be healthy without any sign of reoccurrence. Despite its rare occurrence, our case provides us with a new awareness that thymoma may coexist with MEN1. Oxford University Press 2022-07-08 /pmc/articles/PMC9270031/ /pubmed/35821790 http://dx.doi.org/10.1093/jscr/rjac290 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2022. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Fan, Zheyuan
Wang, Ling
Wang, Jin
Gu, Chundong
Thymoma (World Health Organization Type AB) in multiple endocrine neoplasia type 1: a case report
title Thymoma (World Health Organization Type AB) in multiple endocrine neoplasia type 1: a case report
title_full Thymoma (World Health Organization Type AB) in multiple endocrine neoplasia type 1: a case report
title_fullStr Thymoma (World Health Organization Type AB) in multiple endocrine neoplasia type 1: a case report
title_full_unstemmed Thymoma (World Health Organization Type AB) in multiple endocrine neoplasia type 1: a case report
title_short Thymoma (World Health Organization Type AB) in multiple endocrine neoplasia type 1: a case report
title_sort thymoma (world health organization type ab) in multiple endocrine neoplasia type 1: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270031/
https://www.ncbi.nlm.nih.gov/pubmed/35821790
http://dx.doi.org/10.1093/jscr/rjac290
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