Antibacterial potency of type VI amidase effector toxins is dependent on substrate topology and cellular context

Members of the bacterial T6SS amidase effector (Tae) superfamily of toxins are delivered between competing bacteria to degrade cell wall peptidoglycan. Although Taes share a common substrate, they exhibit distinct antimicrobial potency across different competitor species. To investigate the molecula...

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Detalles Bibliográficos
Autores principales: Radkov, Atanas, Sapiro, Anne L, Flores, Sebastian, Henderson, Corey, Saunders, Hayden, Kim, Rachel, Massa, Steven, Thompson, Samuel, Mateusiak, Chase, Biboy, Jacob, Zhao, Ziyi, Starita, Lea M, Hatleberg, William L, Vollmer, Waldemar, Russell, Alistair B, Simorre, Jean-Pierre, Anthony-Cahill, Spencer, Brzovic, Peter, Hayes, Beth, Chou, Seemay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270033/
https://www.ncbi.nlm.nih.gov/pubmed/35762582
http://dx.doi.org/10.7554/eLife.79796

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