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Nrf2 Knockout Affected the Ferroptosis Signaling Pathway against Cisplatin-Induced Hair Cell-Like HEI-OC1 Cell Death

Cisplatin is a well-known and widely used anticancer drug with high therapeutic efficacy in solid tumors; however, side effects are common with its use. Because cisplatin can be retained in the cochlea, ototoxicity leading to hearing loss limits its clinical applications. Here, we report that Nrf2 k...

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Detalles Bibliográficos
Autores principales: Wang, Weilong, Ma, Pengwei, Gao, Wei, Lu, Peiheng, Ding, Xuerui, Chen, Jiawei, Yuan, Hao, Lu, Lianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270153/
https://www.ncbi.nlm.nih.gov/pubmed/35814275
http://dx.doi.org/10.1155/2022/2210733