Delineating a serotonin 1B receptor circuit for appetite suppression in mice

Triptans are a class of commonly prescribed antimigraine drugs. Here, we report a previously unrecognized role for them to suppress appetite in mice. In particular, frovatriptan treatment reduces food intake and body weight in diet-induced obese mice. Moreover, the anorectic effect depends on the se...

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Detalles Bibliográficos
Autores principales: Li, Li, Wyler, Steven C., León-Mercado, Luis A., Xu, Baijie, Oh, Youjin, Swati, Chen, Xiameng, Wan, Rong, Arnold, Amanda G., Jia, Lin, Wang, Guanlin, Nautiyal, Katherine, Hen, René, Sohn, Jong-Woo, Liu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270184/
https://www.ncbi.nlm.nih.gov/pubmed/35796804
http://dx.doi.org/10.1084/jem.20212307

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