Cargando…
The Frequency of Rh Phenotype and Its Probable Genotype
Aims and objectives: Our goal is to disseminate data on the distribution pattern of Rh antigen, its phenotypes, and the likely genotypes of these genetic variants in the Pakistani population. Methodology: This study was a cross-sectional research project. Patients’ demographic statistics, such as ag...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270189/ https://www.ncbi.nlm.nih.gov/pubmed/35812560 http://dx.doi.org/10.7759/cureus.25775 |
_version_ | 1784744406203498496 |
---|---|
author | Tariq, Faryal Ashfaq, Javeria Ahmed, Rehana Fatima, Naveena Ahmed, Yumna Borhany, Munira |
author_facet | Tariq, Faryal Ashfaq, Javeria Ahmed, Rehana Fatima, Naveena Ahmed, Yumna Borhany, Munira |
author_sort | Tariq, Faryal |
collection | PubMed |
description | Aims and objectives: Our goal is to disseminate data on the distribution pattern of Rh antigen, its phenotypes, and the likely genotypes of these genetic variants in the Pakistani population. Methodology: This study was a cross-sectional research project. Patients’ demographic statistics, such as age and gender, were gathered from their medical information. Blood group, disease, RhD, and other antigen frequency, phenotype, and probable genotype were considered variables. All blood samples were phenotyped for Rhesus antigens (D, C, c, E, and e), and the test was carried out using the tubing technique. Results: According to gender distribution, most of the patients were males, with 131 frequencies (57.7%), while females had 42.35%. The most common phenotype was DCCee, with its probable genotype DCe/DCe (R1 R1) (34%), followed by DCcee, with probable genotype DCe/ce (R1 r) (29.1%); the least common phenotype was ddCcee, with its probable genotype Ce/ce (r ' r) (0.4%). Conclusion: It is concluded that the DCCee phenotype was the most common with its probable genotype DCe/DCe, while the least common phenotype was ddCcee with its probable genotype Ce/ce. |
format | Online Article Text |
id | pubmed-9270189 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-92701892022-07-09 The Frequency of Rh Phenotype and Its Probable Genotype Tariq, Faryal Ashfaq, Javeria Ahmed, Rehana Fatima, Naveena Ahmed, Yumna Borhany, Munira Cureus Preventive Medicine Aims and objectives: Our goal is to disseminate data on the distribution pattern of Rh antigen, its phenotypes, and the likely genotypes of these genetic variants in the Pakistani population. Methodology: This study was a cross-sectional research project. Patients’ demographic statistics, such as age and gender, were gathered from their medical information. Blood group, disease, RhD, and other antigen frequency, phenotype, and probable genotype were considered variables. All blood samples were phenotyped for Rhesus antigens (D, C, c, E, and e), and the test was carried out using the tubing technique. Results: According to gender distribution, most of the patients were males, with 131 frequencies (57.7%), while females had 42.35%. The most common phenotype was DCCee, with its probable genotype DCe/DCe (R1 R1) (34%), followed by DCcee, with probable genotype DCe/ce (R1 r) (29.1%); the least common phenotype was ddCcee, with its probable genotype Ce/ce (r ' r) (0.4%). Conclusion: It is concluded that the DCCee phenotype was the most common with its probable genotype DCe/DCe, while the least common phenotype was ddCcee with its probable genotype Ce/ce. Cureus 2022-06-09 /pmc/articles/PMC9270189/ /pubmed/35812560 http://dx.doi.org/10.7759/cureus.25775 Text en Copyright © 2022, Tariq et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Preventive Medicine Tariq, Faryal Ashfaq, Javeria Ahmed, Rehana Fatima, Naveena Ahmed, Yumna Borhany, Munira The Frequency of Rh Phenotype and Its Probable Genotype |
title | The Frequency of Rh Phenotype and Its Probable Genotype |
title_full | The Frequency of Rh Phenotype and Its Probable Genotype |
title_fullStr | The Frequency of Rh Phenotype and Its Probable Genotype |
title_full_unstemmed | The Frequency of Rh Phenotype and Its Probable Genotype |
title_short | The Frequency of Rh Phenotype and Its Probable Genotype |
title_sort | frequency of rh phenotype and its probable genotype |
topic | Preventive Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270189/ https://www.ncbi.nlm.nih.gov/pubmed/35812560 http://dx.doi.org/10.7759/cureus.25775 |
work_keys_str_mv | AT tariqfaryal thefrequencyofrhphenotypeanditsprobablegenotype AT ashfaqjaveria thefrequencyofrhphenotypeanditsprobablegenotype AT ahmedrehana thefrequencyofrhphenotypeanditsprobablegenotype AT fatimanaveena thefrequencyofrhphenotypeanditsprobablegenotype AT ahmedyumna thefrequencyofrhphenotypeanditsprobablegenotype AT borhanymunira thefrequencyofrhphenotypeanditsprobablegenotype AT tariqfaryal frequencyofrhphenotypeanditsprobablegenotype AT ashfaqjaveria frequencyofrhphenotypeanditsprobablegenotype AT ahmedrehana frequencyofrhphenotypeanditsprobablegenotype AT fatimanaveena frequencyofrhphenotypeanditsprobablegenotype AT ahmedyumna frequencyofrhphenotypeanditsprobablegenotype AT borhanymunira frequencyofrhphenotypeanditsprobablegenotype |