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Competitive inhibition of the classical complement pathway using exogenous single-chain C1q recognition proteins

Complement component C1q is a protein complex of the innate immune system with well-characterized binding partners that constitutes part of the classical complement pathway. In addition, C1q was recently described in the central nervous system as having a role in synapse elimination both in the heal...

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Detalles Bibliográficos
Autores principales: Vadászi, Henrietta, Kiss, Bence, Micsonai, András, Schlosser, Gitta, Szaniszló, Tamás, Kovács, Réka Á., Györffy, Balázs A., Kékesi, Katalin A., Goto, Yuji, Uzonyi, Barbara, Liliom, Károly, Kardos, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270254/
https://www.ncbi.nlm.nih.gov/pubmed/35690144
http://dx.doi.org/10.1016/j.jbc.2022.102113