Insulin Rescued MCP-1-Suppressed Cholesterol Efflux to Large HDL2 Particles via ABCA1, ABCG1, SR-BI and PI3K/Akt Activation in Adipocytes

PURPOSE: Intracellular cholesterol imbalance plays an important role in adipocyte dysfunction of obesity. However, it is unclear whether obesity induced monocyte chemoattractant protein-1 (MCP-1) causes the adipocyte cholesterol imbalance. In this study, we hypothesize that MCP-1 impairs cholesterol...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Runlu, Fang, Pu, Jiang, Jieyu, Huang, Canxia, Wang, Junjie, Guo, Qi, Li, Hongwei, Wu, Xiaoying, Xie, Xiangkun, Jiang, Yuan, Chen, Qian, Bao, Jinlan, Wang, Jingfeng, Wang, Hong, Zhang, Yuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270268/
https://www.ncbi.nlm.nih.gov/pubmed/33740174
http://dx.doi.org/10.1007/s10557-021-07166-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270268/
https://www.ncbi.nlm.nih.gov/pubmed/33740174
http://dx.doi.org/10.1007/s10557-021-07166-2

Ejemplares similares