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A Bioinformatics Investigation into the Pharmacological Mechanisms of Sodium-Glucose Co-transporter 2 Inhibitors in Diabetes Mellitus and Heart Failure Based on Network Pharmacology
PURPOSE: Diabetes mellitus (DM) is a major risk factor for the development of heart failure (HF). Sodium-glucose co-transporter 2 (SGLT2) inhibitors have demonstrated consistent benefits in the reduction of hospitalization for HF in patients with DM. However, the pharmacological mechanism is not cle...
Autores principales: | Mai, Ziling, Li, Huanqiang, Chen, Guanzhong, Chen, Enzhao, Liu, Liwei, Lun, Zhubin, Lai, Wenguang, Zhou, Chunyun, Yu, Sijia, Liu, Jin, Chen, Shiqun, Chen, Jiyan, Liu, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270285/ https://www.ncbi.nlm.nih.gov/pubmed/34028657 http://dx.doi.org/10.1007/s10557-021-07186-y |
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