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Dental anomaly detection using intraoral photos via deep learning

Children with orofacial clefting (OFC) present with a wide range of dental anomalies. Identifying these anomalies is vital to understand their etiology and to discern the complex phenotypic spectrum of OFC. Such anomalies are currently identified using intra-oral exams by dentists, a costly and time...

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Autores principales: Ragodos, Ronilo, Wang, Tong, Padilla, Carmencita, Hecht, Jacqueline T., Poletta, Fernando A., Orioli, Iêda M., Buxó, Carmen J., Butali, Azeez, Valencia-Ramirez, Consuelo, Restrepo Muñeton, Claudia, Wehby, George L., Weinberg, Seth M., Marazita, Mary L., Moreno Uribe, Lina M., Howe, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270352/
https://www.ncbi.nlm.nih.gov/pubmed/35804050
http://dx.doi.org/10.1038/s41598-022-15788-1
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author Ragodos, Ronilo
Wang, Tong
Padilla, Carmencita
Hecht, Jacqueline T.
Poletta, Fernando A.
Orioli, Iêda M.
Buxó, Carmen J.
Butali, Azeez
Valencia-Ramirez, Consuelo
Restrepo Muñeton, Claudia
Wehby, George L.
Weinberg, Seth M.
Marazita, Mary L.
Moreno Uribe, Lina M.
Howe, Brian J.
author_facet Ragodos, Ronilo
Wang, Tong
Padilla, Carmencita
Hecht, Jacqueline T.
Poletta, Fernando A.
Orioli, Iêda M.
Buxó, Carmen J.
Butali, Azeez
Valencia-Ramirez, Consuelo
Restrepo Muñeton, Claudia
Wehby, George L.
Weinberg, Seth M.
Marazita, Mary L.
Moreno Uribe, Lina M.
Howe, Brian J.
author_sort Ragodos, Ronilo
collection PubMed
description Children with orofacial clefting (OFC) present with a wide range of dental anomalies. Identifying these anomalies is vital to understand their etiology and to discern the complex phenotypic spectrum of OFC. Such anomalies are currently identified using intra-oral exams by dentists, a costly and time-consuming process. We claim that automating the process of anomaly detection using deep neural networks (DNNs) could increase efficiency and provide reliable anomaly detection while potentially increasing the speed of research discovery. This study characterizes the use of` DNNs to identify dental anomalies by training a DNN model using intraoral photographs from the largest international cohort to date of children with nonsyndromic OFC and controls (OFC1). In this project, the intraoral images were submitted to a Convolutional Neural Network model to perform multi-label multi-class classification of 10 dental anomalies. The network predicts whether an individual exhibits any of the 10 anomalies and can do so significantly faster than a human rater can. For all but three anomalies, F1 scores suggest that our model performs competitively at anomaly detection when compared to a dentist with 8 years of clinical experience. In addition, we use saliency maps to provide a post-hoc interpretation for our model’s predictions. This enables dentists to examine and verify our model’s predictions.
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spelling pubmed-92703522022-07-10 Dental anomaly detection using intraoral photos via deep learning Ragodos, Ronilo Wang, Tong Padilla, Carmencita Hecht, Jacqueline T. Poletta, Fernando A. Orioli, Iêda M. Buxó, Carmen J. Butali, Azeez Valencia-Ramirez, Consuelo Restrepo Muñeton, Claudia Wehby, George L. Weinberg, Seth M. Marazita, Mary L. Moreno Uribe, Lina M. Howe, Brian J. Sci Rep Article Children with orofacial clefting (OFC) present with a wide range of dental anomalies. Identifying these anomalies is vital to understand their etiology and to discern the complex phenotypic spectrum of OFC. Such anomalies are currently identified using intra-oral exams by dentists, a costly and time-consuming process. We claim that automating the process of anomaly detection using deep neural networks (DNNs) could increase efficiency and provide reliable anomaly detection while potentially increasing the speed of research discovery. This study characterizes the use of` DNNs to identify dental anomalies by training a DNN model using intraoral photographs from the largest international cohort to date of children with nonsyndromic OFC and controls (OFC1). In this project, the intraoral images were submitted to a Convolutional Neural Network model to perform multi-label multi-class classification of 10 dental anomalies. The network predicts whether an individual exhibits any of the 10 anomalies and can do so significantly faster than a human rater can. For all but three anomalies, F1 scores suggest that our model performs competitively at anomaly detection when compared to a dentist with 8 years of clinical experience. In addition, we use saliency maps to provide a post-hoc interpretation for our model’s predictions. This enables dentists to examine and verify our model’s predictions. Nature Publishing Group UK 2022-07-08 /pmc/articles/PMC9270352/ /pubmed/35804050 http://dx.doi.org/10.1038/s41598-022-15788-1 Text en © The Author(s) 2022, corrected publication 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Ragodos, Ronilo
Wang, Tong
Padilla, Carmencita
Hecht, Jacqueline T.
Poletta, Fernando A.
Orioli, Iêda M.
Buxó, Carmen J.
Butali, Azeez
Valencia-Ramirez, Consuelo
Restrepo Muñeton, Claudia
Wehby, George L.
Weinberg, Seth M.
Marazita, Mary L.
Moreno Uribe, Lina M.
Howe, Brian J.
Dental anomaly detection using intraoral photos via deep learning
title Dental anomaly detection using intraoral photos via deep learning
title_full Dental anomaly detection using intraoral photos via deep learning
title_fullStr Dental anomaly detection using intraoral photos via deep learning
title_full_unstemmed Dental anomaly detection using intraoral photos via deep learning
title_short Dental anomaly detection using intraoral photos via deep learning
title_sort dental anomaly detection using intraoral photos via deep learning
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270352/
https://www.ncbi.nlm.nih.gov/pubmed/35804050
http://dx.doi.org/10.1038/s41598-022-15788-1
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