Cardiac disruption of SDHAF4-mediated mitochondrial complex II assembly promotes dilated cardiomyopathy

Succinate dehydrogenase, which is known as mitochondrial complex II, has proven to be a fascinating machinery, attracting renewed and increased interest in its involvement in human diseases. Herein, we find that succinate dehydrogenase assembly factor 4 (SDHAF4) is downregulated in cardiac muscle in...

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Detalles Bibliográficos
Autores principales: Wang, Xueqiang, Zhang, Xing, Cao, Ke, Zeng, Mengqi, Fu, Xuyang, Zheng, Adi, Zhang, Feng, Gao, Feng, Zou, Xuan, Li, Hao, Li, Min, Lv, Weiqiang, Xu, Jie, Long, Jiangang, Zang, Weijin, Chen, Jinghai, Ding, Jian, Liu, Jiankang, Feng, Zhihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270418/
https://www.ncbi.nlm.nih.gov/pubmed/35803927
http://dx.doi.org/10.1038/s41467-022-31548-1

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