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Lipolysis regulates major transcriptional programs in brown adipocytes
β-Adrenergic signaling is a core regulator of brown adipocyte function stimulating both lipolysis and transcription of thermogenic genes, thereby expanding the capacity for oxidative metabolism. We have used pharmacological inhibitors and a direct activator of lipolysis to acutely modulate the activ...
Autores principales: | Markussen, Lasse K., Rondini, Elizabeth A., Johansen, Olivia Sveidahl, Madsen, Jesper G. S., Sustarsic, Elahu G., Marcher, Ann-Britt, Hansen, Jacob B., Gerhart-Hines, Zachary, Granneman, James G., Mandrup, Susanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270495/ https://www.ncbi.nlm.nih.gov/pubmed/35803907 http://dx.doi.org/10.1038/s41467-022-31525-8 |
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