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KIF24 depletion induces clustering of supernumerary centrosomes in PDAC cells

Clustering of supernumerary centrosomes, which potentially leads to cell survival and chromosomal instability, is frequently observed in cancers. However, the molecular mechanisms that control centrosome clustering remain largely unknown. The centrosomal kinesin KIF24 was previously shown to restrai...

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Detalles Bibliográficos
Autores principales: Mashima, Yu, Nohira, Hayato, Sugihara, Hiroki, Dynlacht, Brian David, Kobayashi, Tetsuo, Itoh, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270500/
https://www.ncbi.nlm.nih.gov/pubmed/35803737
http://dx.doi.org/10.26508/lsa.202201470