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Feasibility Study of a Novel Transcatheter Tricuspid Annuloplasty System in a Porcine Model
Gradually, more attention has been paid to tricuspid regurgitation. Formerly the “forgotten valvular heart disease,” it has been recognized as having high incidence and adverse prognosis if untreated. However, isolated tricuspid valve surgery carries substantial risk and is thus not recommended. The...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270588/ https://www.ncbi.nlm.nih.gov/pubmed/35818503 http://dx.doi.org/10.1016/j.jacbts.2022.02.022 |
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author | Pan, Wenzhi Long, Yuliang Zhang, Xiaochun Chen, Shasha Li, Wei Pan, Cuizhen Guo, Yingqiang Zhou, Daxin Ge, Junbo |
author_facet | Pan, Wenzhi Long, Yuliang Zhang, Xiaochun Chen, Shasha Li, Wei Pan, Cuizhen Guo, Yingqiang Zhou, Daxin Ge, Junbo |
author_sort | Pan, Wenzhi |
collection | PubMed |
description | Gradually, more attention has been paid to tricuspid regurgitation. Formerly the “forgotten valvular heart disease,” it has been recognized as having high incidence and adverse prognosis if untreated. However, isolated tricuspid valve surgery carries substantial risk and is thus not recommended. The K-Clip transcatheter tricuspid annuloplasty system has recently emerged as a minimally invasive therapeutic option that may help address these unmet clinical needs. The K-Clip technology simulates the Kay’s procedure, which reduces the dimensions of the tricuspid annulus by folding and clamping the tricuspid annulus issue with a rigid clamping device. The feasibility of the K-Clip technology was investigated in this study, and annulus area reduction and declining tricuspid regurgitation grades were noted following the procedure. The findings of this study suggest that the K-Clip system may potentially be applicable as a novel transcatheter tricuspid annuloplasty device for the treatment of severe tricuspid in humans. |
format | Online Article Text |
id | pubmed-9270588 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-92705882022-07-10 Feasibility Study of a Novel Transcatheter Tricuspid Annuloplasty System in a Porcine Model Pan, Wenzhi Long, Yuliang Zhang, Xiaochun Chen, Shasha Li, Wei Pan, Cuizhen Guo, Yingqiang Zhou, Daxin Ge, Junbo JACC Basic Transl Sci Preclinical Research Gradually, more attention has been paid to tricuspid regurgitation. Formerly the “forgotten valvular heart disease,” it has been recognized as having high incidence and adverse prognosis if untreated. However, isolated tricuspid valve surgery carries substantial risk and is thus not recommended. The K-Clip transcatheter tricuspid annuloplasty system has recently emerged as a minimally invasive therapeutic option that may help address these unmet clinical needs. The K-Clip technology simulates the Kay’s procedure, which reduces the dimensions of the tricuspid annulus by folding and clamping the tricuspid annulus issue with a rigid clamping device. The feasibility of the K-Clip technology was investigated in this study, and annulus area reduction and declining tricuspid regurgitation grades were noted following the procedure. The findings of this study suggest that the K-Clip system may potentially be applicable as a novel transcatheter tricuspid annuloplasty device for the treatment of severe tricuspid in humans. Elsevier 2022-06-15 /pmc/articles/PMC9270588/ /pubmed/35818503 http://dx.doi.org/10.1016/j.jacbts.2022.02.022 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Preclinical Research Pan, Wenzhi Long, Yuliang Zhang, Xiaochun Chen, Shasha Li, Wei Pan, Cuizhen Guo, Yingqiang Zhou, Daxin Ge, Junbo Feasibility Study of a Novel Transcatheter Tricuspid Annuloplasty System in a Porcine Model |
title | Feasibility Study of a Novel Transcatheter Tricuspid Annuloplasty System in a Porcine Model |
title_full | Feasibility Study of a Novel Transcatheter Tricuspid Annuloplasty System in a Porcine Model |
title_fullStr | Feasibility Study of a Novel Transcatheter Tricuspid Annuloplasty System in a Porcine Model |
title_full_unstemmed | Feasibility Study of a Novel Transcatheter Tricuspid Annuloplasty System in a Porcine Model |
title_short | Feasibility Study of a Novel Transcatheter Tricuspid Annuloplasty System in a Porcine Model |
title_sort | feasibility study of a novel transcatheter tricuspid annuloplasty system in a porcine model |
topic | Preclinical Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270588/ https://www.ncbi.nlm.nih.gov/pubmed/35818503 http://dx.doi.org/10.1016/j.jacbts.2022.02.022 |
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