Ginsenoside compound K reduces the progression of Huntington's disease via the inhibition of oxidative stress and overactivation of the ATM/AMPK pathway

BACKGROUND: Huntington's disease (HD) is a neurodegenerative disorder caused by the expansion of trinucleotide CAG repeat in the Huntingtin (Htt) gene. The major pathogenic pathways underlying HD involve the impairment of cellular energy homeostasis and DNA damage in the brain. The protein kina...

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Detalles Bibliográficos
Autores principales: Hua, Kuo-Feng, Chao, A-Ching, Lin, Ting-Yu, Chen, Wan-Tze, Lee, Yu-Chieh, Hsu, Wan-Han, Lee, Sheau-Long, Wang, Hsin-Min, Yang, Ding-I., Ju, Tz-Chuen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270658/
https://www.ncbi.nlm.nih.gov/pubmed/35818427
http://dx.doi.org/10.1016/j.jgr.2021.11.003

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