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J-SPACE: a Julia package for the simulation of spatial models of cancer evolution and of sequencing experiments

BACKGROUND: The combined effects of biological variability and measurement-related errors on cancer sequencing data remain largely unexplored. However, the spatio-temporal simulation of multi-cellular systems provides a powerful instrument to address this issue. In particular, efficient algorithmic...

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Detalles Bibliográficos
Autores principales: Angaroni, Fabrizio, Guidi, Alessandro, Ascolani, Gianluca, d’Onofrio, Alberto, Antoniotti, Marco, Graudenzi, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270769/
https://www.ncbi.nlm.nih.gov/pubmed/35804300
http://dx.doi.org/10.1186/s12859-022-04779-8