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Orexin-A Reverse Bone Mass Loss Induced by Chronic Intermittent Hypoxia Through OX1R-Nrf2/HIF-1α Pathway

BACKGROUND: Recent studies suggest that there is a potential connection between obstructive sleep apnea (OSA) and osteoporosis through dysregulation of bone metabolism. Orexin-A, a neuroprotective peptide secreted by the hypothalamus, is at a lower level in the plasma of OSA patients, which regulate...

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Detalles Bibliográficos
Autores principales:	Gu, Hong, Ru, Yiwen, Wang, Wei, Cai, Guanhui, Gu, Lanxin, Ye, Junjie, Zhang, Wei-Bing, Wang, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270907/ https://www.ncbi.nlm.nih.gov/pubmed/35818538 http://dx.doi.org/10.2147/DDDT.S363286

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