An Acid-Sensitive Nanofiber Conjugate Based on a Short Aromatic Peptide for Targeted Delivery of Doxorubicin in Liver Cancer

PURPOSE: This study aimed to construct a DOX conjugate with liver tumor targeting and acid sensitivity based on a short aromatic peptide FFYEE, which could amplify the tumor inhibition efficacy of DOX and alleviate tissue toxicity. METHODS: A novel DOX-peptide conjugate, D-gal-FFYEE-hyd-DOX, was con...

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Detalles Bibliográficos
Autores principales: Liang, Ju, Guo, Runfa, Xuan, Maosong, Sun, Qiankun, Wu, Wenlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270908/
https://www.ncbi.nlm.nih.gov/pubmed/35818401
http://dx.doi.org/10.2147/IJN.S359642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270908/
https://www.ncbi.nlm.nih.gov/pubmed/35818401
http://dx.doi.org/10.2147/IJN.S359642

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