Severe Case of Cholestatic Hepatitis From Amoxicillin/Clavulanic Acid

The incidence of amoxicillin/clavulanate (Augmentin) induced liver injury is relatively low when compared to other medications. Amoxicillin/clavulanic acid is one of the most frequently prescribed antibiotics by physicians and is used to treat various bacterial infections. However, amoxicillin/clavu...

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Autores principales: Goyal, Lokesh, Madabhushi, Anirudh K, Siddiqi, Mariam S, Kale, Santosh, Mallick, Deobrat C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Family/General Practice
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270929/
https://www.ncbi.nlm.nih.gov/pubmed/35812609
http://dx.doi.org/10.7759/cureus.25797
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author Goyal, Lokesh
Madabhushi, Anirudh K
Siddiqi, Mariam S
Kale, Santosh
Mallick, Deobrat C
author_facet Goyal, Lokesh
Madabhushi, Anirudh K
Siddiqi, Mariam S
Kale, Santosh
Mallick, Deobrat C
author_sort Goyal, Lokesh
collection PubMed
description The incidence of amoxicillin/clavulanate (Augmentin) induced liver injury is relatively low when compared to other medications. Amoxicillin/clavulanic acid is one of the most frequently prescribed antibiotics by physicians and is used to treat various bacterial infections. However, amoxicillin/clavulanate can cause severe side effects, usually gastrointestinal like nausea and vomiting, rash, and sometimes hematologic like thrombocytopenia. Here, we present a case report where a 63-year-old male treated for a dog bite with amoxicillin/clavulanate acid four weeks ago presents to the hospital with severe cholestatic hepatitis, nausea, and pruritis.
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spelling pubmed-92709292022-07-09 Severe Case of Cholestatic Hepatitis From Amoxicillin/Clavulanic Acid Goyal, Lokesh Madabhushi, Anirudh K Siddiqi, Mariam S Kale, Santosh Mallick, Deobrat C Cureus Family/General Practice The incidence of amoxicillin/clavulanate (Augmentin) induced liver injury is relatively low when compared to other medications. Amoxicillin/clavulanic acid is one of the most frequently prescribed antibiotics by physicians and is used to treat various bacterial infections. However, amoxicillin/clavulanate can cause severe side effects, usually gastrointestinal like nausea and vomiting, rash, and sometimes hematologic like thrombocytopenia. Here, we present a case report where a 63-year-old male treated for a dog bite with amoxicillin/clavulanate acid four weeks ago presents to the hospital with severe cholestatic hepatitis, nausea, and pruritis. Cureus 2022-06-09 /pmc/articles/PMC9270929/ /pubmed/35812609 http://dx.doi.org/10.7759/cureus.25797 Text en Copyright © 2022, Goyal et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Family/General Practice
Goyal, Lokesh
Madabhushi, Anirudh K
Siddiqi, Mariam S
Kale, Santosh
Mallick, Deobrat C
Severe Case of Cholestatic Hepatitis From Amoxicillin/Clavulanic Acid
title Severe Case of Cholestatic Hepatitis From Amoxicillin/Clavulanic Acid
title_full Severe Case of Cholestatic Hepatitis From Amoxicillin/Clavulanic Acid
title_fullStr Severe Case of Cholestatic Hepatitis From Amoxicillin/Clavulanic Acid
title_full_unstemmed Severe Case of Cholestatic Hepatitis From Amoxicillin/Clavulanic Acid
title_short Severe Case of Cholestatic Hepatitis From Amoxicillin/Clavulanic Acid
title_sort severe case of cholestatic hepatitis from amoxicillin/clavulanic acid
topic Family/General Practice
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270929/
https://www.ncbi.nlm.nih.gov/pubmed/35812609
http://dx.doi.org/10.7759/cureus.25797
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