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A CDK activity buffer ensures mitotic completion

The eukaryotic cell cycle is driven by the activity of cyclin-dependent kinases (CDKs). CDK activity rises over 50-fold during the cell cycle, from a low level in G1 to a high level in mitosis. However, it is not known whether the entire range of CDK activity is necessary for cell cycle progression,...

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Detalles Bibliográficos
Autores principales: Basu, Souradeep, Patterson, James O., Zeisner, Theresa U., Nurse, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9270952/
https://www.ncbi.nlm.nih.gov/pubmed/35726599
http://dx.doi.org/10.1242/jcs.259626