Differentiation and homeostasis of effector Treg cells are regulated by inositol polyphosphates modulating Ca(2+) influx

Activated Foxp3(+) regulatory T (Treg) cells differentiate into effector Treg (eTreg) cells to maintain peripheral immune homeostasis and tolerance. T cell receptor (TCR)–mediated induction and regulation of store-operated Ca(2+) entry (SOCE) is essential for eTreg cell differentiation and function....

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Detalles Bibliográficos
Autores principales: Min, Hyungyu, Kim, Wooseob, Hong, Sehoon, Lee, Sungkyu, Jeong, Jinguk, Kim, Seyun, Seong, Rho H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271192/
https://www.ncbi.nlm.nih.gov/pubmed/35776543
http://dx.doi.org/10.1073/pnas.2121520119

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