Cargando…

Hassall’s corpuscles with cellular-senescence features maintain IFNα production through neutrophils and pDC activation in the thymus

Hassall’s corpuscles (HCs) are composed of cornifying, terminally differentiated medullary thymic epithelial cells (mTECs) that are developed under the control of Aire. Here, we demonstrated that HC-mTECs show features of cellular senescence and produce inflammatory cytokines and chemokines includin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jianwei, Sekai, Miho, Matsui, Takeshi, Fujii, Yosuke, Matsumoto, Mitsuru, Takeuchi, Osamu, Minato, Nagahiro, Hamazaki, Yoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271218/ https://www.ncbi.nlm.nih.gov/pubmed/30534943 http://dx.doi.org/10.1093/intimm/dxy073

Ejemplares similares

Polymorphism of Hassall's corpuscles in thymus of human fetuses
por: Asghar, Adil, et al.
Publicado: (2012)

AUTOPLASTIC THYMUS TRANSPLANTS : II. WITH PARTICULAR REFERENCE TO THE REGENERATION OF THE RETICULUM CELLS AND THE FORMATION OF HASSALL'S CORPUSCLES.
por: Jaffe, Henry L.
Publicado: (1926)

Gender-Related Effect of Sodium Dichloroacetate on the Number of Hassall's Corpuscles and RNA NKCC1 Expression in Rat Thymus
por: Stanevičiūtė, Jūratė, et al.
Publicado: (2019)

Thymic Hassall’s corpuscles in Nandanam chicken - light and electronmicroscopic perspective (Gallus domesticus)
por: Kannan, Thandavan Arthanari, et al.
Publicado: (2015)

Post-Aire Medullary Thymic Epithelial Cells and Hassall’s Corpuscles as Inducers of Tonic Pro-Inflammatory Microenvironment
por: Laan, Martti, et al.
Publicado: (2021)

Implications of post-translational modifications of IRF7 on pDC IFN-alpha response
por: Griesbeck, M, et al.
Publicado: (2012)

pDC therapy induces recovery from EAE by recruiting endogenous pDC to sites of CNS inflammation
por: Duraes, Fernanda V., et al.
Publicado: (2016)

Ribavirin Contributes to Hepatitis C Virus Suppression by Augmenting pDC Activation and Type 1 IFN Production
por: Wang, Yang, et al.
Publicado: (2015)

Physiology and pathology of T-cell aging
por: Minato, Nagahiro, et al.
Publicado: (2020)

Selective expression of claudin-5 in thymic endothelial cells regulates the blood–thymus barrier and T-cell export
por: Nagatake, Takahiro, et al.
Publicado: (2020)

Ectopic lamellar Pacinian corpuscle within the thymus. Atypical or abnormal location?
por: Varga, Ivan, et al.
Publicado: (2020)

IFN-α Regulates Blimp-1 Expression via miR-23a and miR-125b in Both Monocytes-Derived DC and pDC
por: Parlato, Stefania, et al.
Publicado: (2013)

What Makes a pDC: Recent Advances in Understanding Plasmacytoid DC Development and Heterogeneity
por: Musumeci, Andrea, et al.
Publicado: (2019)

Enteroendocrine Cells Are Specifically Marked by Cell Surface Expression of Claudin-4 in Mouse Small Intestine
por: Nagatake, Takahiro, et al.
Publicado: (2014)

Rap1 signal modulators control the maintenance of hematopoietic progenitors in bone marrow and adult long‐term hematopoiesis
por: Imai, Takahiko, et al.
Publicado: (2019)

Heterogeneous Escape from X Chromosome Inactivation Results in Sex Differences in Type I IFN Responses at the Single Human pDC Level
por: Hagen, Sven Hendrik, et al.
Publicado: (2020)

Facilitation of β Selection and Modification of Positive Selection in the Thymus of Pd-1–Deficient Mice
por: Nishimura, Hiroyuki, et al.
Publicado: (2000)

Evaluation of hepatic antioxidant capacities of Spirogyra neglecta (Hassall) Kützing in rats
por: Thumvijit, Tarika, et al.
Publicado: (2013)

Claudin-4 Deficiency Results in Urothelial Hyperplasia and Lethal Hydronephrosis
por: Fujita, Harumi, et al.
Publicado: (2012)

Relb acts downstream of medullary thymic epithelial stem cells and is essential for the emergence of RANK(+) medullary epithelial progenitors
por: Baik, Song, et al.
Publicado: (2016)

OA011-05. TLR-mediated pDC responses to HIV-1 ligands
por: Chang, J, et al.
Publicado: (2009)

Primary Human mDC1, mDC2, and pDC Dendritic Cells Are Differentially Infected and Activated by Respiratory Syncytial Virus
por: Johnson, Teresa R., et al.
Publicado: (2011)

Is the White Blood Corpuscle and the Pus Corpuscle Identical?
por: Smith, T. Curtis
Publicado: (1875)

Ikaros cooperates with Notch activation and antagonizes TGFβ signaling to promote pDC development
por: Mastio, Jérôme, et al.
Publicado: (2018)

Monocytes Exposed to Immune Complexes Reduce pDC Type 1 Interferon Response to Vidutolimod
por: Sabree, Shakoora A., et al.
Publicado: (2021)

O19 - Changes in the balance between myeloid (mDC) and plasmacytoid (pDC) cell numbers in peripheral blood during childhood
por: Maggina, Paraskevi, et al.
Publicado: (2014)

Respiratory Syncytial Virus Induced Type I IFN Production by pDC Is Regulated by RSV-Infected Airway Epithelial Cells, RSV-Exposed Monocytes and Virus Specific Antibodies
por: Schijf, Marcel A., et al.
Publicado: (2013)

Effect of in vivo Hydroxychloroquine and ex vivo Anti-BDCA2 mAb Treatment on pDC IFNα Production From Patients Affected With Cutaneous Lupus Erythematosus
por: Gardet, Agnes, et al.
Publicado: (2019)

The appeal of the PDC program
por: Wasow, Thomas
Publicado: (2013)

Microbiota induces tonic CCL2 systemic levels that control pDC trafficking in steady state
por: Swiecki, Melissa, et al.
Publicado: (2016)

On Atmospheric Corpuscles
por: Pouchet, F. M.
Publicado: (1861)

On the Identity of the White Corpuscles of the Blood, with the Salivary Pus, and Mucous Corpuscles
por: Richardson, Joseph
Publicado: (1870)

The Dox-pDC - A murine conditionally immortalized plasmacytoid dendritic cell line with native immune profile
por: Thieme, Sebastian, et al.
Publicado: (2018)

NK-pDC cross-talk leads to the generation of mTRAIL+IFN-α+cytotoxic pDCs following HIV-1 infection of pDCs. Consequences on the control of viral replication
por: Saïdi, Héla, et al.
Publicado: (2010)

Brain Transcriptome Analysis Links Deficiencies of Stress-Responsive Proteins to the Pathomechanism of Kii ALS/PDC
por: Morimoto, Satoru, et al.
Publicado: (2020)

Antioxidant and Renoprotective Effects of Spirogyra neglecta (Hassall) Kützing Extract in Experimental Type 2 Diabetic Rats
por: Ontawong, Atcharaporn, et al.
Publicado: (2013)

On White Blood Corpuscles
por: Hunter, Walter K.
Publicado: (1898)

Plasticity of Blood Corpuscles
Publicado: (1864)

Syphilis-Corpuscles (Selected)
Publicado: (1872)

The Formation of Blood-Corpuscles
Publicado: (1882)

Cannot write session to /tmp/vufind_sessions/sess_osl2v71io3a188fcqut8b5ku4b