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Two lymphoid cell lines potently silence unintegrated HIV-1 DNAs

Mammalian cells mount a variety of defense mechanisms against invading viruses to prevent or reduce infection. One such defense is the transcriptional silencing of incoming viral DNA, including the silencing of unintegrated retroviral DNA in most cells. Here, we report that the lymphoid cell lines K...

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Detalles Bibliográficos
Autores principales: Geis, Franziska K., Kelenis, Demetra P., Goff, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271240/
https://www.ncbi.nlm.nih.gov/pubmed/35810297
http://dx.doi.org/10.1186/s12977-022-00602-7

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