Calreticulin nuclear translocalization alleviates CaM/CaMKII/CREB signaling pathway to enhance chemosensitivity in HDAC inhibitor-resistant hepatocellular carcinoma cells

Calreticulin (CRT) is located in the endoplasmic reticulum (ER), it helps proteins fold correctly inside the ER, and acts as a modulator of Ca(2+) homeostasis. Aberrant expression of CRT is implicated in several cancer types, qualifying CRT as a potential therapeutic target. However, it remains uncl...

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Detalles Bibliográficos
Autores principales: Liu, Yi-Sheng, Chang, Yu-Chun, Kuo, Wei-Wen, Chen, Ming-Cheng, Wang, Tso-Fu, Chen, Tung-Sheng, Lin, Yueh-Min, Li, Chi-Cheng, Liao, Po-Hsiang, Huang, Chih-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271289/
https://www.ncbi.nlm.nih.gov/pubmed/35724265
http://dx.doi.org/10.18632/aging.204131

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