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Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil

BACKGROUND: Oral and oropharyngeal cancer (OPC) is an important cause of morbidity and mortality worldwide. Populations in situations of social vulnerability tend to have higher incidences of cancer, a higher proportion of late diagnosis, greater difficulties in accessing health services, and, conse...

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Autores principales: Ramos, Letícia Francine Silva, Sobrinho, Adriano Referino da Silva, Ribeiro, Lucas Nascimento, Martins-de-Barros, Allan Vinícius, Maurício, Herika Arruda, Ferreira, Stefânia Jeronimo, Carvalho, Marianne de Vasconcelos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271347/
https://www.ncbi.nlm.nih.gov/pubmed/35368007
http://dx.doi.org/10.4317/medoral.25334
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author Ramos, Letícia Francine Silva
Sobrinho, Adriano Referino da Silva
Ribeiro, Lucas Nascimento
Martins-de-Barros, Allan Vinícius
Maurício, Herika Arruda
Ferreira, Stefânia Jeronimo
Carvalho, Marianne de Vasconcelos
author_facet Ramos, Letícia Francine Silva
Sobrinho, Adriano Referino da Silva
Ribeiro, Lucas Nascimento
Martins-de-Barros, Allan Vinícius
Maurício, Herika Arruda
Ferreira, Stefânia Jeronimo
Carvalho, Marianne de Vasconcelos
author_sort Ramos, Letícia Francine Silva
collection PubMed
description BACKGROUND: Oral and oropharyngeal cancer (OPC) is an important cause of morbidity and mortality worldwide. Populations in situations of social vulnerability tend to have higher incidences of cancer, a higher proportion of late diagnosis, greater difficulties in accessing health services, and, consequently, worse prognosis. The aim of this study was to evaluate the relationship between race/skin color and OPC prognosis in Brazil. MATERIAL AND METHODS: This is a cross-sectional epidemiological study using OPC data from the National Cancer Institute between the years 2000 and 2019. The selected variables were: gender, race/skin color, age, education, smoking and alcohol consumption, stage of the disease and disease status at the end of the 1st treatment. RESULTS: 154,214 cases were recorded. Black men, in the 6th decade of life, were the most affected population. Blacks had a lower level of education when compared to non-blacks (p<0.001). Blacks were more exposed to smoking and alcohol consumption (p<0.001). At the time of diagnosis, the black population was at the most advanced stage when compared to non-blacks (p<0.001). At the end of the 1st treatment, more black patients had disease in progression, as well as more black patients died (p<0.001). CONCLUSIONS: Blacks had a worse prognosis for OPC in Brazil. Despite the limitations, these results are important to elucidate the scenario of health disparities in relation to the race/skin color of the Brazilian population. Key words:Head and neck, oncology, cancer, oral cavity, oropharynx.
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spelling pubmed-92713472022-07-11 Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil Ramos, Letícia Francine Silva Sobrinho, Adriano Referino da Silva Ribeiro, Lucas Nascimento Martins-de-Barros, Allan Vinícius Maurício, Herika Arruda Ferreira, Stefânia Jeronimo Carvalho, Marianne de Vasconcelos Med Oral Patol Oral Cir Bucal Research BACKGROUND: Oral and oropharyngeal cancer (OPC) is an important cause of morbidity and mortality worldwide. Populations in situations of social vulnerability tend to have higher incidences of cancer, a higher proportion of late diagnosis, greater difficulties in accessing health services, and, consequently, worse prognosis. The aim of this study was to evaluate the relationship between race/skin color and OPC prognosis in Brazil. MATERIAL AND METHODS: This is a cross-sectional epidemiological study using OPC data from the National Cancer Institute between the years 2000 and 2019. The selected variables were: gender, race/skin color, age, education, smoking and alcohol consumption, stage of the disease and disease status at the end of the 1st treatment. RESULTS: 154,214 cases were recorded. Black men, in the 6th decade of life, were the most affected population. Blacks had a lower level of education when compared to non-blacks (p<0.001). Blacks were more exposed to smoking and alcohol consumption (p<0.001). At the time of diagnosis, the black population was at the most advanced stage when compared to non-blacks (p<0.001). At the end of the 1st treatment, more black patients had disease in progression, as well as more black patients died (p<0.001). CONCLUSIONS: Blacks had a worse prognosis for OPC in Brazil. Despite the limitations, these results are important to elucidate the scenario of health disparities in relation to the race/skin color of the Brazilian population. Key words:Head and neck, oncology, cancer, oral cavity, oropharynx. Medicina Oral S.L. 2022-07 2022-04-03 /pmc/articles/PMC9271347/ /pubmed/35368007 http://dx.doi.org/10.4317/medoral.25334 Text en Copyright: © 2022 Medicina Oral S.L. https://creativecommons.org/licenses/by/2.5/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Ramos, Letícia Francine Silva
Sobrinho, Adriano Referino da Silva
Ribeiro, Lucas Nascimento
Martins-de-Barros, Allan Vinícius
Maurício, Herika Arruda
Ferreira, Stefânia Jeronimo
Carvalho, Marianne de Vasconcelos
Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil
title Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil
title_full Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil
title_fullStr Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil
title_full_unstemmed Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil
title_short Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil
title_sort racial disparity and prognosis in patients with mouth and oropharynx cancer in brazil
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271347/
https://www.ncbi.nlm.nih.gov/pubmed/35368007
http://dx.doi.org/10.4317/medoral.25334
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