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Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil
BACKGROUND: Oral and oropharyngeal cancer (OPC) is an important cause of morbidity and mortality worldwide. Populations in situations of social vulnerability tend to have higher incidences of cancer, a higher proportion of late diagnosis, greater difficulties in accessing health services, and, conse...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medicina Oral S.L.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271347/ https://www.ncbi.nlm.nih.gov/pubmed/35368007 http://dx.doi.org/10.4317/medoral.25334 |
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author | Ramos, Letícia Francine Silva Sobrinho, Adriano Referino da Silva Ribeiro, Lucas Nascimento Martins-de-Barros, Allan Vinícius Maurício, Herika Arruda Ferreira, Stefânia Jeronimo Carvalho, Marianne de Vasconcelos |
author_facet | Ramos, Letícia Francine Silva Sobrinho, Adriano Referino da Silva Ribeiro, Lucas Nascimento Martins-de-Barros, Allan Vinícius Maurício, Herika Arruda Ferreira, Stefânia Jeronimo Carvalho, Marianne de Vasconcelos |
author_sort | Ramos, Letícia Francine Silva |
collection | PubMed |
description | BACKGROUND: Oral and oropharyngeal cancer (OPC) is an important cause of morbidity and mortality worldwide. Populations in situations of social vulnerability tend to have higher incidences of cancer, a higher proportion of late diagnosis, greater difficulties in accessing health services, and, consequently, worse prognosis. The aim of this study was to evaluate the relationship between race/skin color and OPC prognosis in Brazil. MATERIAL AND METHODS: This is a cross-sectional epidemiological study using OPC data from the National Cancer Institute between the years 2000 and 2019. The selected variables were: gender, race/skin color, age, education, smoking and alcohol consumption, stage of the disease and disease status at the end of the 1st treatment. RESULTS: 154,214 cases were recorded. Black men, in the 6th decade of life, were the most affected population. Blacks had a lower level of education when compared to non-blacks (p<0.001). Blacks were more exposed to smoking and alcohol consumption (p<0.001). At the time of diagnosis, the black population was at the most advanced stage when compared to non-blacks (p<0.001). At the end of the 1st treatment, more black patients had disease in progression, as well as more black patients died (p<0.001). CONCLUSIONS: Blacks had a worse prognosis for OPC in Brazil. Despite the limitations, these results are important to elucidate the scenario of health disparities in relation to the race/skin color of the Brazilian population. Key words:Head and neck, oncology, cancer, oral cavity, oropharynx. |
format | Online Article Text |
id | pubmed-9271347 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Medicina Oral S.L. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92713472022-07-11 Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil Ramos, Letícia Francine Silva Sobrinho, Adriano Referino da Silva Ribeiro, Lucas Nascimento Martins-de-Barros, Allan Vinícius Maurício, Herika Arruda Ferreira, Stefânia Jeronimo Carvalho, Marianne de Vasconcelos Med Oral Patol Oral Cir Bucal Research BACKGROUND: Oral and oropharyngeal cancer (OPC) is an important cause of morbidity and mortality worldwide. Populations in situations of social vulnerability tend to have higher incidences of cancer, a higher proportion of late diagnosis, greater difficulties in accessing health services, and, consequently, worse prognosis. The aim of this study was to evaluate the relationship between race/skin color and OPC prognosis in Brazil. MATERIAL AND METHODS: This is a cross-sectional epidemiological study using OPC data from the National Cancer Institute between the years 2000 and 2019. The selected variables were: gender, race/skin color, age, education, smoking and alcohol consumption, stage of the disease and disease status at the end of the 1st treatment. RESULTS: 154,214 cases were recorded. Black men, in the 6th decade of life, were the most affected population. Blacks had a lower level of education when compared to non-blacks (p<0.001). Blacks were more exposed to smoking and alcohol consumption (p<0.001). At the time of diagnosis, the black population was at the most advanced stage when compared to non-blacks (p<0.001). At the end of the 1st treatment, more black patients had disease in progression, as well as more black patients died (p<0.001). CONCLUSIONS: Blacks had a worse prognosis for OPC in Brazil. Despite the limitations, these results are important to elucidate the scenario of health disparities in relation to the race/skin color of the Brazilian population. Key words:Head and neck, oncology, cancer, oral cavity, oropharynx. Medicina Oral S.L. 2022-07 2022-04-03 /pmc/articles/PMC9271347/ /pubmed/35368007 http://dx.doi.org/10.4317/medoral.25334 Text en Copyright: © 2022 Medicina Oral S.L. https://creativecommons.org/licenses/by/2.5/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Ramos, Letícia Francine Silva Sobrinho, Adriano Referino da Silva Ribeiro, Lucas Nascimento Martins-de-Barros, Allan Vinícius Maurício, Herika Arruda Ferreira, Stefânia Jeronimo Carvalho, Marianne de Vasconcelos Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil |
title | Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil |
title_full | Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil |
title_fullStr | Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil |
title_full_unstemmed | Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil |
title_short | Racial disparity and prognosis in patients with mouth and oropharynx cancer in Brazil |
title_sort | racial disparity and prognosis in patients with mouth and oropharynx cancer in brazil |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271347/ https://www.ncbi.nlm.nih.gov/pubmed/35368007 http://dx.doi.org/10.4317/medoral.25334 |
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