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Targeting STT3A produces an anti-tumor effect in lung adenocarcinoma by blocking the MAPK and PI3K/AKT signaling pathway
BACKGROUND: Glycosylation is crucial for the stability and biological functions of proteins. The aberrant glycosylation of critical proteins plays an important role in multiple cancers, including lung adenocarcinoma (LUAD). STT3 oligosaccharyltransferase complex catalytic subunit A (STT3A) is a majo...
Autores principales: | Cheng, Jiahan, Xia, Liang, Hao, Xiaohu, Gan, Fanyi, Bai, Yuquan, Zhang, Chuanfen, Mao, Yonghong, Zhu, Yunke, Pu, Qiang, Park, Dong Won, Tavolari, Simona, Mei, Jiandong, Chen, Yaohui, Deng, Senyi, Liu, Lunxu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271429/ https://www.ncbi.nlm.nih.gov/pubmed/35832442 http://dx.doi.org/10.21037/tlcr-22-396 |
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