Metformin Attenuates Cardiac Hypertrophy Via the HIF-1α/PPAR-γ Signaling Pathway in High-Fat Diet Rats

Coronary artery disease (CAD) and cardiac hypertrophy (CH) are two main causes of ischemic heart disease. Acute CAD may lead to left ventricular hypertrophy (LVH). Long-term and sustained CH is harmful and can gradually develop into cardiac insufficiency and heart failure. It is known that metformin...

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Detalles Bibliográficos
Autores principales: Liu, Yuansheng, Zhang, Qian, Yang, Lei, Tian, Wencong, Yang, Yinan, Xie, Yuhang, Li, Jing, Yang, Liang, Gao, Yang, Xu, Yang, Liu, Jie, Wang, Yachen, Yan, Jie, Li, Guoxun, Shen, Yanna, Qi, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271627/
https://www.ncbi.nlm.nih.gov/pubmed/35833024
http://dx.doi.org/10.3389/fphar.2022.919202

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