Cargando…

Brain Activation During Processing of Depression Emotion in College Students With Premenstrual Syndrome in China: Preliminary Findings

BACKGROUND: This study aimed to investigate the neural substrates of processing depression emotion in premenstrual syndrome (PMS) and healthy subjects of college students using blood oxygenation level-dependent functional magnetic resonance imaging (BOLD-fMRI). METHODS: During BOLD-fMRI scanning, 13...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Mingzhou, An, Li, Yu, Yanhong, Wang, Jieqiong, Hou, Yanjiao, Xu, Qiuqi, Ren, Lvning, Gao, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271695/
https://www.ncbi.nlm.nih.gov/pubmed/35832597
http://dx.doi.org/10.3389/fpsyt.2022.856443
_version_ 1784744724949630976
author Gao, Mingzhou
An, Li
Yu, Yanhong
Wang, Jieqiong
Hou, Yanjiao
Xu, Qiuqi
Ren, Lvning
Gao, Dongmei
author_facet Gao, Mingzhou
An, Li
Yu, Yanhong
Wang, Jieqiong
Hou, Yanjiao
Xu, Qiuqi
Ren, Lvning
Gao, Dongmei
author_sort Gao, Mingzhou
collection PubMed
description BACKGROUND: This study aimed to investigate the neural substrates of processing depression emotion in premenstrual syndrome (PMS) and healthy subjects of college students using blood oxygenation level-dependent functional magnetic resonance imaging (BOLD-fMRI). METHODS: During BOLD-fMRI scanning, 13 PMS patients and 15 healthy controls (HC) performed a picture visual stimulation task during luteal and follicular phases, in which participants and HC were asked to see pictures containing depression and non-depression emotions. Simultaneously, self-rating depression scales (SDS) were employed to evaluate the emotional status of participants. RESULTS: Compared to HC, right inferior occipital gyrus, right middle occipital gyrus, right lingual gyrus, right fusiform gyrus, right inferior temporal gyrus, cerebelum_crus1_R, cerebelum_6_R, culmen, the cerebellum anterior lobe, tuber, and cerebellar tonsil of PMS patients showed enhanced activation. In contrast, sub-lobar, sub-gyral, extra-nuclear, right orbit part of superior frontal gyrus, right middle temporal gyrus, right orbit part of inferior frontal gyrus, limbic lobe, right insula, bilateral anterior and adjacent cingulate gyrus, bilateral caudate, caudate head, bilateral putamen, and left globus pallidus exhibited decreased activation. CONCLUSION: The findings indicate that abnormal functional regulation of brain regions such as occipital lobe and cerebellum leads to abnormal changes in emotional regulation, cognitive ability, and attention distribution in PMS patients, implying significant central pathogenesis.
format Online
Article
Text
id pubmed-9271695
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-92716952022-07-12 Brain Activation During Processing of Depression Emotion in College Students With Premenstrual Syndrome in China: Preliminary Findings Gao, Mingzhou An, Li Yu, Yanhong Wang, Jieqiong Hou, Yanjiao Xu, Qiuqi Ren, Lvning Gao, Dongmei Front Psychiatry Psychiatry BACKGROUND: This study aimed to investigate the neural substrates of processing depression emotion in premenstrual syndrome (PMS) and healthy subjects of college students using blood oxygenation level-dependent functional magnetic resonance imaging (BOLD-fMRI). METHODS: During BOLD-fMRI scanning, 13 PMS patients and 15 healthy controls (HC) performed a picture visual stimulation task during luteal and follicular phases, in which participants and HC were asked to see pictures containing depression and non-depression emotions. Simultaneously, self-rating depression scales (SDS) were employed to evaluate the emotional status of participants. RESULTS: Compared to HC, right inferior occipital gyrus, right middle occipital gyrus, right lingual gyrus, right fusiform gyrus, right inferior temporal gyrus, cerebelum_crus1_R, cerebelum_6_R, culmen, the cerebellum anterior lobe, tuber, and cerebellar tonsil of PMS patients showed enhanced activation. In contrast, sub-lobar, sub-gyral, extra-nuclear, right orbit part of superior frontal gyrus, right middle temporal gyrus, right orbit part of inferior frontal gyrus, limbic lobe, right insula, bilateral anterior and adjacent cingulate gyrus, bilateral caudate, caudate head, bilateral putamen, and left globus pallidus exhibited decreased activation. CONCLUSION: The findings indicate that abnormal functional regulation of brain regions such as occipital lobe and cerebellum leads to abnormal changes in emotional regulation, cognitive ability, and attention distribution in PMS patients, implying significant central pathogenesis. Frontiers Media S.A. 2022-06-27 /pmc/articles/PMC9271695/ /pubmed/35832597 http://dx.doi.org/10.3389/fpsyt.2022.856443 Text en Copyright © 2022 Gao, An, Yu, Wang, Hou, Xu, Ren and Gao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Gao, Mingzhou
An, Li
Yu, Yanhong
Wang, Jieqiong
Hou, Yanjiao
Xu, Qiuqi
Ren, Lvning
Gao, Dongmei
Brain Activation During Processing of Depression Emotion in College Students With Premenstrual Syndrome in China: Preliminary Findings
title Brain Activation During Processing of Depression Emotion in College Students With Premenstrual Syndrome in China: Preliminary Findings
title_full Brain Activation During Processing of Depression Emotion in College Students With Premenstrual Syndrome in China: Preliminary Findings
title_fullStr Brain Activation During Processing of Depression Emotion in College Students With Premenstrual Syndrome in China: Preliminary Findings
title_full_unstemmed Brain Activation During Processing of Depression Emotion in College Students With Premenstrual Syndrome in China: Preliminary Findings
title_short Brain Activation During Processing of Depression Emotion in College Students With Premenstrual Syndrome in China: Preliminary Findings
title_sort brain activation during processing of depression emotion in college students with premenstrual syndrome in china: preliminary findings
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271695/
https://www.ncbi.nlm.nih.gov/pubmed/35832597
http://dx.doi.org/10.3389/fpsyt.2022.856443
work_keys_str_mv AT gaomingzhou brainactivationduringprocessingofdepressionemotionincollegestudentswithpremenstrualsyndromeinchinapreliminaryfindings
AT anli brainactivationduringprocessingofdepressionemotionincollegestudentswithpremenstrualsyndromeinchinapreliminaryfindings
AT yuyanhong brainactivationduringprocessingofdepressionemotionincollegestudentswithpremenstrualsyndromeinchinapreliminaryfindings
AT wangjieqiong brainactivationduringprocessingofdepressionemotionincollegestudentswithpremenstrualsyndromeinchinapreliminaryfindings
AT houyanjiao brainactivationduringprocessingofdepressionemotionincollegestudentswithpremenstrualsyndromeinchinapreliminaryfindings
AT xuqiuqi brainactivationduringprocessingofdepressionemotionincollegestudentswithpremenstrualsyndromeinchinapreliminaryfindings
AT renlvning brainactivationduringprocessingofdepressionemotionincollegestudentswithpremenstrualsyndromeinchinapreliminaryfindings
AT gaodongmei brainactivationduringprocessingofdepressionemotionincollegestudentswithpremenstrualsyndromeinchinapreliminaryfindings