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Construction and Application of Polygenic Risk Scores in Autoimmune Diseases

Genome-wide association studies (GWAS) have identified hundreds of genetic variants associated with autoimmune diseases and provided unique mechanistic insights and informed novel treatments. These individual genetic variants on their own typically confer a small effect of disease risk with limited...

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Detalles Bibliográficos
Autores principales:	Khunsriraksakul, Chachrit, Markus, Havell, Olsen, Nancy J., Carrel, Laura, Jiang, Bibo, Liu, Dajiang J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271862/ https://www.ncbi.nlm.nih.gov/pubmed/35833142 http://dx.doi.org/10.3389/fimmu.2022.889296

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