Th2 to Th1 Transition Is Required for Induction of Skin Lesions in an Inducible and Recurrent Murine Model of Cutaneous Lupus–Like Inflammation

Cutaneous lupus erythematosus (CLE) is an autoimmune skin disease characterized by a strong IFN signature, normally associated with type I IFNs. However, increasing evidence points to an additional role for IFNγ, or at least a pathogenic T effector subset dependent on IFNγ, for disease progression....

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Detalles Bibliográficos
Autores principales: Haddadi, Nazgol-Sadat, Mande, Purvi, Brodeur, Tia Y., Hao, Kaiyuan, Ryan, Grace E., Moses, Stephanie, Subramanian, Sharon, Picari, Xhuliana, Afshari, Khashayar, Marshak-Rothstein, Ann, Richmond, Jillian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271959/
https://www.ncbi.nlm.nih.gov/pubmed/35833127
http://dx.doi.org/10.3389/fimmu.2022.883375

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