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Nicotinamide Mononucleotide Administration Triggers Macrophages Reprogramming and Alleviates Inflammation During Sepsis Induced by Experimental Peritonitis

Peritonitis and subsequent sepsis lead to high morbidity and mortality in response to uncontrolled systemic inflammation primarily mediated by macrophages. Nicotinamide adenine dinucleotide (NAD+) is an important regulator of oxidative stress and immunoinflammatory responses. However, the effects of...

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Detalles Bibliográficos
Autores principales: Cros, Cécile, Margier, Marielle, Cannelle, Hélène, Charmetant, Julie, Hulo, Nicolas, Laganier, Laurent, Grozio, Alessia, Canault, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271973/
https://www.ncbi.nlm.nih.gov/pubmed/35832733
http://dx.doi.org/10.3389/fmolb.2022.895028